Evidence map›Paper›PMID 41895721›Full record

ReviewEuropean heart journal2026

Tricuspid regurgitation: standardized stepwise work-up from referral to expert heart valve centre.

Julien Dreyfus, Fabien Praz, Rebecca Hahn, Davide Margonato, Denisa Muraru, David Messika-Zeitoun, Marianna Adamo, Eustachio Agricola, Erwan Donal, Mirjam Wild and 11 more

Abstract readReview
In one paragraph

Review in European heart journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Julien DreyfusDepartment of Cardiology, Centre Cardiologique du Nord, 32-36 rue de smoulins gémeaux, 93200 Saint-Denis, France.ORCID 0000-0003-1338-3007
Fabien PrazDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0001-5416-165X
Rebecca HahnDivision of Cardiology, Columbia University Medical Center, NewYork, NY, USA.
Davide MargonatoCardiovascular Imaging Research Center, Minneapolis Heart Institute and Foundation, Minneapolis, MN, USA.
Denisa MuraruDepartment of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.ORCID 0000-0003-2514-3668
David Messika-ZeitounDivision of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.ORCID 0000-0002-6278-5670
Marianna AdamoCardiac Catheterization Laboratory and Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.ORCID 0000-0002-3855-1815
Eustachio AgricolaCardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-4834-2187
Erwan DonalUniversity of Rennes, CHU Rennes, Inserm, LTSI-UMR 1099, Rennes, France.ORCID 0000-0003-2677-3389
Mirjam WildDepartment of Cardiology and Angiology, Medical Center, Faculty of Medicine, University Heart Center, University of Freiburg, Freiburg, Germany.
Haran BurriCardiology Department, University Hospital of Geneva, Geneva, Switzerland.
Marco MetraCardiology, Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milan, Italy.ORCID 0000-0001-6691-8568
Augustin CoisneUniv. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France.
Karl-Patrik KresojaDepartment of Cardiology, University Medical Center, Johannes Gutenberg University, Mainz, Germany.ORCID 0000-0002-8616-6751
Julia GrapsaDepartment of Cardiology, Heart and Vascular Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4620-6234
Jeroen BaxDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-7368-0500
Marta SitgesDepartment of Cardiology, Cardiovascular Institute, Hospital Clínic, Universitat de Barcelona, IDIBAPS, CIBERCV, Instituto de Salud Carlos III, Barcelona, Spain.ORCID 0000-0003-1300-4732
Bernard PrendergastDepartment of Cardiology, Cleveland Clinic London, London, UK.
Francesco MaisanoIRCCS Ospedale San Raffaele, Università Vita Salute, Milan, Italy.
Joao CavalcanteCardiovascular Imaging Research Center, Minneapolis Heart Institute and Foundation, Minneapolis, MN, USA.
Nina Ajmone MarsanDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tricuspid regurgitation (TR) is a common yet historically neglected condition associated with poor outcomes. Traditionally managed conservatively, TR has recently gained renewed attention, thanks to advances in surgical and transcatheter interventions. Selecting the optimal therapy, however, requires an integrated and systematic approach considering TR aetiology, stage of the disease, comorbidities, operative risk, and anatomical feasibility. This review describes a standardized stepwise work-up for patients with TR from the referral centre to the expert heart valve centre (HVC). It provides practical algorithms and structured protocols covering clinical and biological assessment, multimodality imaging (echocardiography, computed tomography, cardiac magnetic resonance), and invasive haemodynamic evaluation. The document highlights the importance of multidisciplinary collaboration, involving imagers, heart failure specialists, interventional cardiologists, electrophysiologists, and surgeons, in line with the new recommendations of the 2025 ESC/EACTS Guidelines for the Management of Valvular Heart Disease. By harmonizing diagnostic standards and promoting a structured approach to patient assessment within HVCs, this review aims to facilitate timely referral and ensure consistent evaluation and management of patients with this complex and often underestimated condition.

Indexed as

Referral and ConsultationTricuspid Valve InsufficiencyEchocardiographyHumansMultimodal ImagingHeart valve centreInterventionsMultimodality imagingRight heartTricuspid regurgitation

Identifiers

PMID41895721
PMCPMC13446990

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.