ArticleScience advances2026
Unraveling branch point-driven SR45a splicing dynamics in heat stress for plant adaptation.
Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Alternative Splicing of SCL30a Generates Distinct Isoforms to Modulate ABA Signaling in Arabidopsis.Plants (Basel, Switzerland) · 2026Article
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Authors and funding
11 authors.
Funding
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Abstract
Heat stress impairs plant development by disrupting essential molecular processes. Alternative splicing (AS) is emerging as a key regulatory mechanism in heat responses, yet how stress-responsive AS is fine-tuned within core splicing regulators remains underexplored. Here, we uncover a heat-activated, autoregulatory splicing switch in the serine/arginine-rich factor SR45a, critically dependent on intron 4. Using an intron 4-based luciferase reporter, we show that heat enhances intron removal, promoting the full-length isoform over truncated variants. This switch relies on branch point (BP) recognition, with SR45a and cap-binding protein 20 (CBP20) coordinating BP-dependent splicing under stress. Overexpression of either protein enhances thermotolerance by stabilizing AS dynamics. HSFA2 directly activates
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