Evidence map›Paper›PMID 41894139›Full record

ArticleCardiovascular engineering and technology2026

Mechanical Behavior of Valve Stents in Diverse Bicuspid Aortic Valves: Influence of Structural Design and Annular Eccentricity.

Xiang Shen, Huilin Yao, Zewen He, Yizhe Wang, Yue Xu, Qiang Liu, Jiahao Chen, Jianwei Gao, Lei Wang, Yan Wang and 1 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Cardiovascular engineering and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiang ShenSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China. sx@ujs.edu.cn.ORCID 0000-0003-2235-980X
Huilin YaoSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Zewen HeSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Yizhe WangSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Yue XuSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Qiang LiuSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Jiahao ChenSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Jianwei GaoSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Lei WangSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Yan WangSchool of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, China.
Hongyu LiangInstitute of Advanced Manufacturing and Modern Equipment Technology,School of Mechanical Engineering , Jiangsu University, Zhenjiang, 212013, China.

Funding

National Natural Science Foundation of China 52375187Natural Science Foundation of Jiangsu Province BK20130525Natural Science Foundation of the Higher Education Institutions of Jiangsu Province 13KJB460006
6 · The paper itself

Abstract

objectiveTo evaluate the expansion mechanics of transcatheter heart valves in bicuspid aortic valve (BAV)anatomies, quantifying the infl uence of stent design and annular eccentricity.

methodsFinite element simulations were performed to compare two self-expanding (E, V) and one balloon-expandable (S) stent across four BAV morphologies (Type 0, LR, LN, RN) with varying annular eccentricity (0.2-0.4).Key metrics included post-implant stent ellipticity, stent stress, and aortic wall stress.

resultsThe eccentricity of the valve stent after implantation increased with the increase of the eccentricity of theBAV valve ring. Among the four BAV types, the balloon-expandable stent (S-stent) showed higher stent stress andaortic wall stress than the self-expanding stent, but its expansion uniformity was the best. The analysis reveals afundamental trade-off between achieving optimal expansion uniformity and minimizing implant-induced stress.

conclusionThis study provides a biomechanical framework for personalized stent selection in BAV-TAVR, indicatingthat the choice of the optimal device depends on the priority given to specifi c clinical outcomes (such as sealingvs.long-term durability).

Indexed as

Aortic ValveHeart Valve DiseasesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationStentsBicuspid Aortic Valve DiseaseComputer SimulationFinite Element AnalysisHumansModels, CardiovascularProsthesis DesignStress, MechanicalAnnular eccentricityBicuspid aortic valveExpansion behaviorStructural designValve stents

Identifiers

PMID41894139

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.