Evidence map›Paper›PMID 41893959›Full record

ArticleVeterinary research communications2026

Normative values of tear film parameters in brachycephalic dogs using OSA-Vet

Jéssica N Voitena, Tatiane O C Marinho, Fabiano Montiani-Ferreira, Daniela N Cremonini, João L V Chiurciu, Nadja S Jesus, Ana P V B Pohle, Olicies da Cunha, Fábio L C Brito

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Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jéssica N VoitenaUniversidade Federal do Paraná (UFPR), Setor Palotina, Palotina, PR, Brazil. jnvoitena@gmail.com.
Tatiane O C MarinhoFaculdade Qualittas, São Paulo, SP, Brazil.
Fabiano Montiani-FerreiraUniversidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
Daniela N CremoniniFaculdade Qualittas, São Paulo, SP, Brazil.
João L V ChiurciuFaculdade Qualittas, São Paulo, SP, Brazil.
Nadja S JesusUniversidade São Judas Tadeu, São Paulo, SP, Brazil.
Ana P V B PohleFaculdade Qualittas, São Paulo, SP, Brazil.
Olicies da CunhaUniversidade Federal do Paraná (UFPR), Setor Palotina, Palotina, PR, Brazil.
Fábio L C BritoFaculdade Qualittas, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The precorneal tear film is critical for ocular surface health, and brachycephalic dogs are particularly predisposed to tear film instability due to their unique conformation. This study aimed to establish normative values for tear film parameters in healthy brachycephalic dogs using the OSA-Vet®, including Schirmer tear test-1 (STT-1), tear meniscus height (TMH), and non-invasive tear breakup time (TBUTNI). Forty brachycephalic dogs (66 eyes) with STT-1 values between 15 and 25 mm/min underwent complete ophthalmological examination and OSA-Vet® evaluation. Data were analyzed for distribution, descriptive statistics, and correlations. Median values were 20 mm/min [19–22] for STT-1, 0.45 mm [0.36–0.62] for TMH, and 1.25 s [0.70–4.00] for TBUTNI. Spearman’s analysis revealed no significant association between STT-1 and TMH (ρ = 0.136, p = 0.277) or between TMH and TBUTNI (ρ = 0.046, p = 0.716). A weak positive correlation was observed between STT-1 and TBUTNI (ρ = 0.256, p = 0.038). These results demonstrate that even in dogs with preserved aqueous tear production, TBUTNI values remain low and variable, highlighting the predisposition of brachycephalic breeds to evaporative instability. TMH showed limited diagnostic value, underscoring the importance of multimodal tear film assessment. Previous studies have used OSA-Vet® to evaluate ocular surface parameters across cephalic conformations. The present study focuses specifically on establishing clinically applicable reference values in phenotypically brachycephalic dogs screened for normal aqueous tear production.

Indexed as

CraniosynostosesDiagnostic Techniques, OphthalmologicalTearsAnimalsDog DiseasesDogsFemaleMaleReference ValuesOcular surface analyzerTear tests

Identifiers

PMID41893959
PMCPMC13031193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.