ArticleJournal of ultrasound2026
Characterization of dermatofibromas and epidermoid cysts using dermoscopy-guided high-frequency ultrasound imaging.
Article in Journal of ultrasound, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeEpidermoid cysts and dermatofibromas may resemble malignant lesions, requiring accurate non-invasive differentiation. Our objective was to assess dermoscopy-guided high-frequency ultrasound (DG-HFUS) in distinguishing these lesions.
methodsNine lesions (four epidermoid cysts, five dermatofibromas) were examined using DG-HFUS with a 33 MHz linear probe in B-mode. The dermoscopic modality guided probe placement. For each lesion, a minimum of 10 consecutive frames were acquired to ensure measurement reproducibility. Lesions were evaluated based on predetermined characteristics.
resultsEpidermoid cysts presented as well-circumscribed, oval lesions located in the dermis or dermal-subcutaneous border, with depths of 1.4-8.7 mm. All showed mixed echogenicity with hyperechoic foci and bands. Dermatofibromas were smaller (2.4-3.5 mm), within the dermis, hypoechoic with scattered hyperechoic areas, poorly defined margins, and 3-5 hypoechoic bands extending into surrounding structures.
conclusionDG-HFUS reliably correlated dermoscopic and sonographic features, enhancing non-invasive diagnosis of benign cutaneous lesions.
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