ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
The forgotten story behind the first published retinal paintings.
Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Sine speculo oculi nulla dictyitidis diagnosis: without an ophthalmoscope, no diagnosis of retinitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messagesWHAT IS KNOWN : • Helmholtz invented the ophthalmoscope in 1850 and published his observations in a monograph in 1851. However, he did not include an illustration of what he observed; • The first published retinal paintings were created in 1853 by the artistically gifted physician Adrien Christophe van Trigt. WHAT IS NEW: • Shortly after Helmholtz's publication of the ophthalmoscope, the Amsterdam instrument maker Epkens designed and constructed a table-model ophthalmoscope that left the dominant hand free; • The ophthalmologist Donders in Utrecht recognized in Epkens' table model ophthalmoscope the opportunity to produce retinal paintings for publication purposes. He recruited the artistically skilled physician Adrien van Trigt as PhD student to carry out this work; • The collaboration of Donders, Van Trigt and Epkens resulted within 19 months following Helmholtz' monograph, in the publication of retinal paintings - a remarkably fast achievement, given that retinal photography was not yet available.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.