Evidence map›Paper›PMID 41893872›Full record

Observational studyKidney3602026

Vascular Access Surgery Timing: A Prospective European Cohort Study in Elderly Patients with ESKD.

Boudewijn D C Heggen, Nicholas C Chesnaye, Friedo W Dekker, Merel van Diepen, Joris I Rotmans, Fergus J Caskey, Claudia Torino, Antonio Vilasi, Maciej Szymczak, Christiane Drechsler and 8 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Kidney360, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Boudewijn D C HeggenDepartment of Vascular Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0001-8978-4128
Nicholas C ChesnayeERA Registry, Department of Medical Informatics, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0003-4883-9174
Friedo W DekkerDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-2433-2494
Merel van DiepenDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-3211-9500
Joris I RotmansDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-9682-6234
Fergus J CaskeyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-5199-3925
Claudia TorinoIFC-CNR, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy.ORCID 0000-0002-4967-0916
Antonio VilasiIFC-CNR, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy.ORCID 0000-0002-9393-2418
Maciej SzymczakClinical Department of Nephrology, Transplantation Medicine and Internal Diseases, Wroclaw Medical University, Wroclaw, Poland.ORCID 0000-0002-1248-081
Christiane DrechslerDivision of Nephrology, Department of Medicine, University of Würzburg, Würzburg, Germany.ORCID 0000-0002-0012-9707
Christoph WannerDepartment of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.ORCID 0000-0001-9507-5301
Maria PippiasPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.ORCID 0000-0001-7469-4955
Kitty J JagerERA Registry, Department of Medical Informatics, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0003-0444-8569
Marie EvansRenal Unit, Department of Clinical Intervention and technology (CLINTEC), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0001-8650-5795
Mickaël HiligsmannDepartment of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-4274-9258
Geert Willem H SchurinkDepartment of Vascular Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands.
Maarten G J SnoeijsDepartment of Vascular Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-4551-2451
EQUAL Study Investigators

Funding

Leading the Change 80-85009-98-2004Nierstichting 20OK016Nierstichting SB 142
6 · The paper itself

Abstract

key pointsOnly 32% of elderly patients with ESKD in Europe started hemodialysis with a functional fistula that was created on time. Vascular access was created early in 42% and late in 26% of patients, exposing these patients to unused fistulas or catheter dependency. Eventually, 90% of all patients after fistula creation started hemodialysis within the mean follow-up period of 30 months.

backgroundTiming vascular access creation for older patients with ESKD is challenging. Autologous arteriovenous fistulas (AVF) are often created too early, leading to unused fistulas, or too late, necessitating central venous catheters (CVC). This study reports on vascular access creation in relation to hemodialysis initiation in European practice.

methodsThis study is a secondary analysis of the European Quality cohort: a prospective observational study that recruited patients aged ≥65 years with stage 4 or 5 CKD from six European countries. Patients were selected once their eGFR dropped below 15 ml/min per 1.73 m 2 , if they received a vascular access, and had at least 6 months of follow-up. Vascular access timing was categorized into three groups: early (no dialysis within 6 months after AVF creation), on time (dialysis initiated with an AVF within 6 months), and late (hemodialysis initiated with a CVC before or within 6 months after AVF creation).

resultsA total of 332 patients from the European Quality cohort were analyzed: 221 patients (67%) received an AVF as first vascular access and 111 patients (33%) a CVC. Among the latter, 53 patients (48%) underwent subsequent AVF creation, whereas for the remaining 58 patients, CVC was considered the intended vascular access strategy. At dialysis initiation, 158 patients (54%) used an AVF, while 136 patients (46%) used a CVC. AVF creation was on time in 88 of 274 patients (32%), early in 114 patients (42%), and late in 72 patients (26%). Despite high rates of early AVF creation, most fistulas were eventually used, as 90% of patients initiated hemodialysis within 3 years.

conclusionsOnly 32% of elderly patients with ESKD started hemodialysis with a functional AVF created on time (within the 6-month window), while 42% had early and 26% late creation. Clinical prediction tools are needed to optimize vascular access timing.

Indexed as

Arteriovenous Shunt, SurgicalKidney Failure, ChronicRenal DialysisAgedAged, 80 and overEuropeFemaleGlomerular Filtration RateHumansMaleProspective StudiesTime Factorsarteriovenous accessclinical trialdialysis accesshemodialysishemodialysis accessvascular access

Identifiers

PMID41893872
PMCPMC13641530

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.