Evidence map›Paper›PMID 41893810›Full record

ArticleVaccines2026

Examining Discordance in Perceptions of COVID-19 and Influenza Vaccine Safety During Pregnancy Among a Cohort of US Adults.

Rachael Piltch-Loeb, Bai Xi Jasmine Chan, Josefina Nuñez Sahr, Chloe Teasdale, Sasha Fleary, Kate Penrose, Jenna Sanborn, Subha Balasubramanian, McKaylee Robertson, Angela Parcesepe

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachael Piltch-LoebInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.
Bai Xi Jasmine ChanInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.
Josefina Nuñez SahrInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.ORCID 0009-0005-1459-836X
Chloe TeasdaleInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.
Sasha FlearyInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.
Kate PenroseInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.ORCID 0000-0002-7808-7439
Jenna SanbornInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.
Subha BalasubramanianInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.
McKaylee RobertsonInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.ORCID 0000-0002-8426-6572
Angela ParcesepeInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY 10027, USA.ORCID 0000-0002-4321-125X

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Brief digital intervention to increase COVID-19 vaccination among individuals with anxiety or depressionRF1MH132360 · NIMH · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI NASH, DENIS, PARCESEPE, ANGELA · 2022 to 2022
$3.3M
National Institute of Allergy and Infectious Diseases UH3AI133675NICHD NIH HHS P2C HD050924NIMH NIH HHS RF1 MH132360NIMH NIH HHS RF1MH132360
6 · The paper itself

Abstract

BACKGROUND/

objectivesVaccination is an important strategy to protect pregnant people, fetuses, and infants from severe influenza and COVID-19. However, as of April 2025 in the United States, only 14% of pregnant women had received the 2024-2025 COVID-19 vaccine, while influenza vaccine uptake among pregnant women was 38% compared to 57% in 2020. Our study assessed the perceived safety of receiving these vaccines during pregnancy within a community-based national cohort.

methodsParticipants reported safety perceptions of vaccination during pregnancy and were categorized as (1) endorsing the safety of both COVID-19 and influenza vaccines, (2) endorsing the safety of only the influenza vaccine, (3) endorsing the safety of only the COVID-19 vaccine and (4) endorsing the safety of neither vaccine during pregnancy. We examined sociodemographics, behaviors, and beliefs correlated with these four categories. Log-binomial models were used to estimate the prevalence ratios of (a) endorsing the safety of only influenza vaccine versus endorsing the safety of both COVID-19 and influenza vaccines during pregnancy, and (b) endorsing safety of neither versus both vaccines during pregnancy.

resultsIn total, 40% of adults (N = 1725) endorsed the safety of both vaccines during pregnancy, 18% (N = 751) endorsed the safety of only the influenza vaccine, 4% (N = 183) endorsed the safety of only the COVID-19 vaccine, and 38% (N = 1621) did not endorse the safety of either vaccine during pregnancy. Participants who were non-Hispanic Black, reported inconsistent vaccination habits, and expressed low trust in government and healthcare providers were more likely to endorse the safety of only the influenza vaccine or neither vaccine compared with endorsing both vaccines.

conclusionsThese findings highlight the need to build trust in the medical system, reduce access barriers, and use equitable, community-driven messaging to strengthen confidence in the safety of receiving the COVID-19 and influenza vaccines during pregnancy.

Indexed as

COVID-19 vaccineinfluenza vaccinepregnancyvaccine hesitancywomen’s health

Identifiers

PMID41893810
PMCPMC13030822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.