Evidence map›Paper›PMID 41893785›Full record

ArticleVaccines2026

Assessment of the Immunogenicity and Safety of an Inactivated Associated Vaccine Against Influenza and Newcastle Disease.

Lespek Kutumbetov, Balzhan Myrzakhmetova, Gulzhan Zhapparova, Talshyn Tlenchiyeva, Ayan Tuyakov, Karina Bissenbayeva, Aruzhan Smagulova

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lespek KutumbetovResearch Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.
Balzhan MyrzakhmetovaResearch Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.
Gulzhan ZhapparovaResearch Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.
Talshyn TlenchiyevaResearch Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.
Ayan TuyakovResearch Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.ORCID 0009-0000-5922-0030
Karina BissenbayevaResearch Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.
Aruzhan SmagulovaResearch Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesCombined vaccination against avian influenza (A/H5N3, A/H7N7) and Newcastle disease is of practical interest for reducing handling during immunization and for achieving timely protection in poultry. The aim of this study was to evaluate an inactivated combined (associated) vaccine containing antigenic variants of avian influenza viruses A/H5N3 and A/H7N7 and Newcastle disease virus (NDV). The vaccine is protected by Patent No. 87417.

methodsViruses with initial reproductive titers of 10

resultsFollowing vaccination, protective immunity was observed starting from day 14. HI titers peaked by day 30 (7.6-7.8 log

conclusionsThe developed inactivated combined vaccine induced HI antibodies and protective immunity against avian influenza (A/H5N3, A/H7N7) and Newcastle disease. The formulation concept supports flexible antigen combinations and enables group administration via drinking water, which may reduce handling compared with separate vaccinations.

Indexed as

aluminum hydroxide gelassociated vaccineavian influenzainactivated combined vaccineNewcastle disease virus (NDV)

Identifiers

PMID41893785
PMCPMC13029891

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.