Evidence map›Paper›PMID 41893712›Full record

ArticleVeterinary sciences2026

Effects of N-Acetylneuraminic Acid on Intestinal Microbial Composition and Metabolic Activity in a Piglet Model.

Jiaqi Zhang, Runhan Ye, Xuan Li, Xiaoyi Liu, Kaifeng Lian, Ran Xu, Yahui Chen, Weiyun Zhu, Kaifan Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaqi ZhangLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Runhan YeLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Xuan LiLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Xiaoyi LiuLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Kaifeng LianLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Ran XuLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yahui ChenLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Weiyun ZhuLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Kaifan YuLaboratory of Gastrointestinal Microbiology, Jiangsu Joint International Research Laboratory of Animal Gastrointestinal Genomes, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-5018-3744

Funding

National Natural Science Foundation of China 32372830National Natural Science Foundation of China U22A20519Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX25_1008
6 · The paper itself

Abstract

This study investigates the effects of N-acetylneuraminic acid (Neu5Ac) on intestinal microbial composition and metabolic activity in piglets using two complementary approaches: in vitro fermentation and in vivo dietary supplementation with coated Neu5Ac. In vitro fermentation results demonstrated that Neu5Ac stimulates higher production of formate and acetate by piglet intestinal microbiota compared with other human milk-derived monosaccharides (

Indexed as

acetateformateintestinal microbiotaNeu5Acpiglets

Identifiers

PMID41893712
PMCPMC13030646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.