Evidence map›Paper›PMID 41893684›Full record

ReviewVeterinary sciences2026

The Potential of Chlorogenic Acid in Regulating Oxidative Damage, Lipid Metabolism, and Inflammation in Chickens: A Comprehensive Review.

Bo Zheng, Xueqing Xiao, Yanli Wang, Dongying Bai, Wenrui Zhen, Fangshen Guo, Bingkun Zhang, Yi Zhang, Yanbo Ma

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bo ZhengDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.ORCID 0009-0009-3264-738X
Xueqing XiaoDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Yanli WangDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Dongying BaiDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Wenrui ZhenDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Fangshen GuoDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Bingkun ZhangState Key Laboratory of Animal Nutrition, Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Yi ZhangDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.ORCID 0000-0002-4773-287X
Yanbo MaDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.

Funding

Financial support statement National Key Research andDevelopment Program of China #2024YFE0111600Key Research and Development Program of Henan Province #241111113800the Frontier exploration Projects of Longmen Laboratory # LMQYTSKT037Trendy Industry Projects of Longmen Laboratory #LMFKCY2023002
6 · The paper itself

Abstract

Heat stress, high stocking density, and feed safety risks are common features of modern intensive poultry production and collectively disrupt metabolic homeostasis in chickens. These stressors promote oxidative stress, lipid metabolic dysfunction, and inflammatory activation, ultimately reducing growth performance and overall health. This review summarizes current evidence on the effects of major stressors under intensive farming conditions on lipid metabolic homeostasis, redox balance, and immune regulatory networks, with particular emphasis on the supplementation strategies and physiological effects of chlorogenic acid (CGA) in chickens. Available studies indicate that CGA may regulate lipid metabolic homeostasis through adenosine monophosphate-activated protein kinase (AMPK)-related signaling pathways, enhance antioxidant defenses mediated by nuclear factor erythroid 2 related factor 2 (Nrf2), and suppress inflammatory responses associated with nuclear factor κB (NF-κB), thereby contributing to protective regulation at multiple levels.

Indexed as

chickenschlorogenic acidinflammationlipid metabolismoxidative stress

Identifiers

PMID41893684
PMCPMC13030064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.