Evidence map›Paper›PMID 41893647›Full record

ArticleVeterinary sciences2026

Assessment of Oxidative Stress and DNA Damage in Dogs with Visceral Leishmaniasis Using Urinary 8-Hydroxy-2'-Deoxyguanosine.

Demet Derya, Songul Erdogan, Tahir Ozalp, Hasan Erdogan, Serdar Pasa, Mehmet Gultekin, Kerem Ural, Ilia Tsachev

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Demet DeryaDepartment of Internal Medicine, Veterinary Faculty, Aydın Adnan Menderes University, Aydın 09016, Türkiye.
Songul ErdoganDepartment of Internal Medicine, Veterinary Faculty, Aydın Adnan Menderes University, Aydın 09016, Türkiye.
Tahir OzalpDepartment of Internal Medicine, Veterinary Faculty, Aydın Adnan Menderes University, Aydın 09016, Türkiye.
Hasan ErdoganDepartment of Internal Medicine, Veterinary Faculty, Aydın Adnan Menderes University, Aydın 09016, Türkiye.ORCID 0000-0001-5141-5108
Serdar PasaDepartment of Internal Medicine, Veterinary Faculty, Aydın Adnan Menderes University, Aydın 09016, Türkiye.
Mehmet GultekinDepartment of Internal Medicine, Veterinary Faculty, Aydın Adnan Menderes University, Aydın 09016, Türkiye.
Kerem UralDepartment of Internal Medicine, Veterinary Faculty, Aydın Adnan Menderes University, Aydın 09016, Türkiye.ORCID 0000-0003-1867-7143
Ilia TsachevDepartment of Clinical Science, Faculty of Veterinary Medicine, Medical University-Pleven, 5800 Pleven, Bulgaria.

Funding

Aydın Adnan Menderes University Research Fund (ADÜ-BAP) VTF-24047Bulgarian Ministry of Education and Science BG-RRP-2.004-0006-C02
6 · The paper itself

Abstract

Canine leishmaniasis (CanL) is a major vector-borne disease with zoonotic potential, and oxidative stress plays an important role in its pathogenesis. CanL is a chronic, progressive disease in which clinical signs may develop gradually over months or even years, depending on host immune response and parasite burden. This study aimed to evaluate oxidative DNA damage in dogs with CanL by measuring urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels and oxidative stress markers. A total of 54 dogs, including 34 dogs with CanL and 20 healthy controls, were included. Urinary 8-OHdG and serum malondialdehyde (MDA) were measured using ELISA method, whereas serum TAC and TOC were determined using automated colorimetric method. Dogs with CanL showed significantly higher TAC (1.30 ± 0.05 vs. 1.04 ± 0.06 mmol/L,

Indexed as

biomarkerDNA damagedogoxidative stressvector born disease

Identifiers

PMID41893647
PMCPMC13030719

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.