Evidence map›Paper›PMID 41893551›Full record

Observational studyToxins2026

Paediatric Snakebite Toxicity up to Compartment Syndrome: A Ten-Year Retrospective Study in Iasi, Romania.

Bogdan Caba, Sidonia Petronela Susanu, Ioana Cezara Caba, Tamara Roșu-Solange, Bogdan Huzum, Vasile Eduard Roșu, Ileana Katerina Ioniuc, Maria Adriana Mocanu, Iuliana Magdalena Starcea

Abstract readObservational Study
In one paragraph

Observational study in Toxins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bogdan CabaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0006-8514-3204
Sidonia Petronela SusanuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Ioana Cezara CabaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-1615-4824
Tamara Roșu-SolangeGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Bogdan HuzumGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Vasile Eduard RoșuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Ileana Katerina IoniucGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Maria Adriana MocanuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Iuliana Magdalena StarceaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-3937-7425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viper bites are medical emergencies that can develop into serious clinical complications and can endanger the life of the paediatric patient. This observational retrospective study analyses 24 cases of viper bites involving paediatric patients (<18 years) encountered over 10 years (2016-2025) in the emergency department of Saint Mary Emergency Hospital of Iasi, Romania, with a focus on those requiring specialised surgical monitoring. Sociodemographic factors, toxicity, and surgical management of snakebites were analysed. In 83.33% cases, viper bites were found on the lower limb. The retrospective study was completed through an in-depth analysis of two representative cases, with a particular focus on the evolution up to compartment syndrome. Of the 24 cases presented in the Emergency Department, one was a rare and severe case, which evolved into compartment syndrome and required fasciotomy to save the limb in the Plastic Surgical Department. Another one, with the bite localised at the upper limb, had perilesional oedema, without skin colour changes or secretions, preservation of joint contours, and normal nail colouration. Both were analysed and described in detail with all available data (images, investigations, etc.) to highlight pathophysiological and therapeutic aspects. Appropriate, multidisciplinary treatment considerably improves the functional prognosis of patients with viper bites; administration of antivenom and selective fasciotomy contribute to successful outcomes. The study emphasises that viper bites in children remain a public health problem in Romania and require prompt and multidisciplinary treatment.

Indexed as

Compartment SyndromesSnake BitesViper VenomsAdolescentAnimalsAntiveninsChildChild, PreschoolFasciotomyFemaleHumansInfantMaleRetrospective StudiesRomaniaViperaAntiveninsViper Venomsantivenomcompartment syndromefasciotomyfunctional limb recoverylocal tissue toxicityplastic surgerysnakebitetoxicology

Identifiers

PMID41893551
PMCPMC13030228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.