Evidence map›Paper›PMID 41893546›Full record

ArticleToxins2026

Molecular Basis of the Inhibition of Voltage-Gated Potassium Channel Kv1.1 by Chinese Tarantula Peptide Huwentoxin-XI.

Xuan Luo, Yuan Yin, Fenghua Wang, Xinyu Li, Shujun Wang, Yumei Yang, Chunbing Zheng, Jing Liu, Meichun Deng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuan LuoHunan Province Key Laboratory of Basic and Applied Hematology, Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha 410013, China.
Yuan YinHunan Province Key Laboratory of Basic and Applied Hematology, Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha 410013, China.
Fenghua WangCollege of Physical Education, Xinjiang Normal University, Urumqi 830054, China.
Xinyu LiXiangya School of Medicine, Central South University, Changsha 410013, China.
Shujun WangHunan Province Key Laboratory of Basic and Applied Hematology, Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha 410013, China.
Yumei YangHunan Province Key Laboratory of Basic and Applied Hematology, Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha 410013, China.
Chunbing ZhengChangsha Institute of Industrial Technology for Stem Cell and Regenerative Medicine, Changsha 410100, China.
Jing LiuHunan Province Key Laboratory of Basic and Applied Hematology, Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha 410013, China.
Meichun DengHunan Province Key Laboratory of Basic and Applied Hematology, Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, Changsha 410013, China.

Funding

Hunan Provincial Key R&D Program 2024JK2137Hunan Provincial Natural Science Foundation of China 2023JJ10082National Natural Science Foundation of China 82071250, 31672290
6 · The paper itself

Abstract

Huwentoxin-XI (HWTX-XI) is a 55-amino acid peptide belonging to the family of spider Kuntiz-type toxins (KTTs), isolated from the venom of the Chinese tarantula

Indexed as

Kv1.1 Potassium ChannelPeptidesPotassium Channel BlockersSpider VenomsAnimalsEast Asian PeopleGanglia, SpinalHumansMaleMiceNeuronsSpidersKv1.1 Potassium ChannelPeptidesPotassium Channel BlockersSpider VenomsKv1.1painpatch-clamppotassium channelstarantula toxin

Identifiers

PMID41893546
PMCPMC13030696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.