Evidence map›Paper›PMID 41893506›Full record

ArticleToxics2026

Brevetoxin PbTx2 Modulates Oxidative Stress and Inflammatory Response in an In Vitro Human Immune Cell Line.

Ambbar Aballay-González, Claudia Melo, Alejandra Rivera, Miquel Martorell, Viviana Ulloa, Juan José Gallardo-Rodriguez, Allisson Astuya-Villalón

Abstract read
In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ambbar Aballay-GonzálezCentro de Investigación Oceanográfica COPAS Sur-Austral, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070386, Chile.ORCID 0000-0002-3810-4695
Claudia MeloCentro de Investigación Oceanográfica COPAS Sur-Austral, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070386, Chile.
Alejandra RiveraCentro de Investigación Oceanográfica COPAS Sur-Austral, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070386, Chile.
Miquel MartorellDepartamento de Nutrición y Dietética, Facultad de Farmacia, Universidad de Concepción, Concepción 4070386, Chile.ORCID 0000-0003-3183-7623
Viviana UlloaLaboratorio de Biotoxinas de la Universidad de Concepción (LBTx-UdeC), Departamento de Oceanografía, Facultad de Ciencias Naturales y Oceanografía, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070386, Chile.
Juan José Gallardo-RodriguezDepartment of Chemical Engineering, Research Centre CIAIMBITAL, University of Almería, 04120 Almería, Spain.ORCID 0000-0003-2953-7699
Allisson Astuya-VillalónCentro de Investigación Oceanográfica COPAS Sur-Austral, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070386, Chile.ORCID 0000-0002-6988-6159

Funding

Agencia Nacional de Investigación y Desarrollo COPAS-COASTAL ANID FB210021Agencia Nacional de Investigación y Desarrollo project FONDECYT REGULAR 1200845Universidad de Concepción Chile VRID Asociativo Nº217.073.033-1.0
6 · The paper itself

Abstract

Brevetoxins (PbTx) exert detrimental effects on marine organisms and humans, mainly through alterations in immune cell function. This study evaluated the immunotoxic potential of sublethal concentrations of PbTx-2 using the THP-1 human monocyte cell line as an in vitro model. Cell viability assessed by the MTT assay revealed an IC

Indexed as

brevetoxin-2cell-based assayharmful algal bloomhuman monocytic cell lineinflammationoxidative stressROS production

Identifiers

PMID41893506
PMCPMC13030196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.