Evidence map›Paper›PMID 41893476›Full record

ArticleToxics2026

Mitochondrial Ultrastructure, Fission Proteins, Activity, and Motor Dysfunctions in the Innovative Parkinson's Disease Model Induced by Manganese Inhalation.

Cesar Alfonso Garcia-Caballero, Jose Luis Ordoñez-Librado, Avril De Alba-Ríos, Enrique Montiel-Flores, Omar Emiliano Aparicio-Trejo, Fernando García-Arroyo, Belén Cuevas-Lopez, José Pedraza-Chaverri, Vianey Rodríguez-Lara, Rocío Tron-Alvarez and 4 more

Abstract read
In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cesar Alfonso Garcia-CaballeroUnidad de Posgrado, Edificio "D", Primer Piso, Cto. de los Posgrados S/N, C.U., Postgraduate Unit, Building "D", First Floor, Postgraduate Circuit S/N, C.U., Coyoacan, Mexico City 04510, Mexico.ORCID 0009-0007-3706-0997
Jose Luis Ordoñez-LibradoNeuromorphology Lab, Faculty of Higher Studies Iztacala, UNAM, Los Reyes Iztacala, Tlalnepantla, Mexico City 54090, Mexico.ORCID 0000-0002-1229-5403
Avril De Alba-RíosNeuromorphology Lab, Faculty of Higher Studies Iztacala, UNAM, Los Reyes Iztacala, Tlalnepantla, Mexico City 54090, Mexico.ORCID 0009-0006-7026-787X
Enrique Montiel-FloresNeuromorphology Lab, Faculty of Higher Studies Iztacala, UNAM, Los Reyes Iztacala, Tlalnepantla, Mexico City 54090, Mexico.ORCID 0000-0001-8319-9710
Omar Emiliano Aparicio-TrejoDepartment of Cardio-Renal Physiopathology, National Institute of Cardiology Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0002-7701-4537
Fernando García-ArroyoDepartment of Cardio-Renal Physiopathology, National Institute of Cardiology Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0003-1545-9765
Belén Cuevas-LopezDepartment of Cardio-Renal Physiopathology, National Institute of Cardiology Ignacio Chávez, Mexico City 14080, Mexico.
José Pedraza-ChaverriFaculty of Chemistry, Department of Biology, UNAM, Mexico City 04510, Mexico.ORCID 0000-0001-6628-4411
Vianey Rodríguez-LaraDepartment of Cell and Tissue Biology, Faculty of Medicine, UNAM, Mexico City 04510, Mexico.
Rocío Tron-AlvarezHealth Education Project, Faculty of Higher Studies Iztacala, UNAM, Mexico City 54090, Mexico.ORCID 0000-0002-8763-8685
Ana Luisa Gutierréz-ValdezNeuromorphology Lab, Faculty of Higher Studies Iztacala, UNAM, Los Reyes Iztacala, Tlalnepantla, Mexico City 54090, Mexico.ORCID 0000-0002-6560-381X
Javier Sánchez-BetancourtNeuromorphology Lab, Faculty of Higher Studies Iztacala, UNAM, Los Reyes Iztacala, Tlalnepantla, Mexico City 54090, Mexico.ORCID 0000-0003-1122-6438
Leonardo Reynoso-ErazoHealth Education Project, Faculty of Higher Studies Iztacala, UNAM, Mexico City 54090, Mexico.ORCID 0000-0001-9793-1431
Maria Rosa Avila-CostaNeuromorphology Lab, Faculty of Higher Studies Iztacala, UNAM, Los Reyes Iztacala, Tlalnepantla, Mexico City 54090, Mexico.ORCID 0000-0002-3000-186X

Funding

CONAHCYT (SECITHI) CBF2023-2024-190FESI-PAPCA-UNAM 2021-2022-32PAPIIT-DGAPA-UNAM IN202725PAPIIT-DGAPA-UNAM IN216525
6 · The paper itself

Abstract

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, yet its pathogenic mechanisms remain incompletely understood, highlighting the need for reliable experimental models. We previously developed a murine model based on inhalation of a manganese mixture (MnCl

Indexed as

animal modelDrp1Fis1manganesemitochondriamitochondrial activityParkinson’s diseaseultrastructure

Identifiers

PMID41893476
PMCPMC13030830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.