Evidence map›Paper›PMID 41893384›Full record

ArticleJACC. Case reports2026

Double LLAMACORN: Bilateral Leaflet Modification Technique to Prevent Coronary Obstruction.

Andrea Ruberti, Laura Sanchis, Omar Abdul-Jawad Altisent, Giovanni Occhipinti, Manel Sabatè-Tenàs, Pedro Cèpas-Guillen, Eduardo Flores-Umanzor, Xavier Freixa, Ander Regueiro

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea RubertiHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain; Bellvitge Universitary Hospital, Barcelona, Catalunya, Spain. Electronic address: anderregueiro@gmail.com.
Laura SanchisHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Omar Abdul-Jawad AltisentHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Giovanni OcchipintiHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Manel Sabatè-TenàsHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Pedro Cèpas-GuillenHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Eduardo Flores-UmanzorHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Xavier FreixaHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Ander RegueiroHospital Clínic, Cardiovascular Clinic Institute, Barcelona, Catalunya, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalunya, Spain; Facultat de Medicina i Ciencies de la Salut, Universitat de Barcelona (UB), Barcelona, Spain. Electronic address: aregueir@clinic.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the double LLAMACORN (Leaflet Laceration with Balloon-Mediated Annihilation to prevent coronary obstruction with radiofrequency needle) procedure as a strategy for bilateral leaflet modification before valve-in-valve transcatheter aortic valve replacement (TAVR) in a patient at high risk for coronary obstruction. KEY STEPS: The right and left leaflets were traversed using electrosurgery. Sequential bileaflet dilatation was performed using coronary balloons and positioning of 2 extra-stiff Safari wires through the leaflets. Sequential bileaflet laceration was achieved with Atlas balloons. A 23-mm Navitor was deployed, with postdilatation as needed. POTENTIAL PITFALLS: Catheter entanglement may occur, particularly in small anatomies. Hemodynamic compromise may result from aortic regurgitation after simultaneous leaflet laceration. TAKE-HOME MESSAGE: Double LLAMACORN is a feasible alternative to BASILICA (bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction), streamlining bilateral leaflet modification and preserving coronary flow.

Indexed as

aortic stenosisBASILICALLAMACORNTAVRvalve-in-valve

Identifiers

PMID41893384
PMCPMC13332656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.