Evidence map›Paper›PMID 41893380›Full record

ArticleJACC. Case reports2026

Hemodynamic Effects of Adjunct Intra-Aortic Balloon Pumping During Veno-Arterial ECMO: A Pressure-Volume Loop Study.

Giulio M Mondellini, Myrthe P J van Steenwijk, Jesse R Kimman, Jesse J Duijghuisen, Paolo Meani, Nicolas M Van Mieghem, Christiaan L Meuwese

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giulio M MondelliniDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Myrthe P J van SteenwijkDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Jesse R KimmanDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Jesse J DuijghuisenDepartment of Anesthesia, Erasmus Medical Center, Rotterdam, the Netherlands.
Paolo MeaniCardiothoracic and Vascular Anesthesia and Intensive Care Unit, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Nicolas M Van MieghemDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Christiaan L MeuweseDepartment of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address: c.meuwese@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere ventriculo-arterial decoupling during veno arterial-extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shock (CS) can be mitigated by adjunct intra-aortic balloon pump (IABP) support. The precise hemodynamic effects of IABP in this setting are however unknown. EARLY REPORT SUMMARY: This case report describes in vivo left ventricular (LV) and right ventricular (RV) pressure-volume (PV) relationships in a young patient on VA-ECMO for CS after out-of-hospital cardiac arrest due to an ST-segment elevation myocardial infarction during a sequential IABP on-off-on protocol, at both low- and high-VA-ECMO flow states. DISCUSSION: Using intracardiac PV loops at the time of VA-ECMO weaning in a patient with refractory CS, we demonstrated that adjunctive IABP: 1) reduced LV and RV afterload; 2) increased native stroke volume; and 3) in the low-flow setting only, coincided with a marked decrease in biventricular end-diastolic pressure. TAKE-HOME MESSAGE: In our patient, invasive PV loop analyses showed that IABP support reduced LV and RV afterload during high-flow V-A ECMO and decreased preload of both ventricles at low VA-ECMO flow.

Indexed as

acute heart failurecardiac assist devicescirculationleft-sided catheterizationleft ventriclemyocardial infarctionright ventricleshortness of breathventricular fibrillation

Identifiers

PMID41893380
PMCPMC13130934

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.