Evidence map›Paper›PMID 41893275›Full record

ReviewMembranes2026

Recent Advances in Stimuli-Responsive Membranes: From Supramolecular Design to Controlled Permeability.

Samanta Moffa, Serena Pilato, Michele Ciulla, Pietro Di Profio, Antonella Fontana, Fabrizio Masciulli, Gabriella Siani

Abstract readReview
In one paragraph

Review in Membranes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samanta MoffaDipartimento di Farmacia, Università "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0003-4940-7701
Serena PilatoDipartimento di Farmacia, Università "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0003-4971-6483
Michele CiullaDipartimento di Farmacia, Università "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-7147-4356
Pietro Di ProfioDipartimento di Farmacia, Università "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-8038-7940
Antonella FontanaDipartimento di Farmacia, Università "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-5391-7520
Fabrizio MasciulliDipartimento di Farmacia, Università "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-4518-534X
Gabriella SianiDipartimento di Farmacia, Università "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0003-0380-367X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimuli-responsive liposomal membranes have attracted growing interest as dynamic soft materials capable of regulating permeability, fusion, and cargo release in response to external or internal triggers. By incorporating functional molecular or nanostructured guests, such as photochromic compounds, plasmonic nanoparticles, or ionizable lipids, bilayers can be endowed with reversible and tunable properties. These modifications often rely on the precise control of lipid packing, phase behaviour, and the formation of transient membrane defects that facilitate molecular transport. This review aims to provide an overview of the molecular design strategies and underlying mechanisms used to engineer such responsive liposomal systems, with particular emphasis on light- and heat-triggered behaviours and on supramolecular approaches that modulate membrane structure and dynamics. Emerging trends, current limitations, and opportunities for future development in functional lipid-based materials and biointerfaces will also be discussed.

Indexed as

lipid bilayer dynamicsmembrane permeability modulationstimuli-responsive liposomes

Identifiers

PMID41893275
PMCPMC13028524

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.