A Facile Nanocarrier for Paclitaxel Delivery Based on Carboxymethyl Chitosan Encapsulated 6-Deoxy-6-Mercapto-β-Cyclodextrin Grafted Concave Cubic Gold.

Hao Li, Lin Zhang, You Long, Chao Shen, Song Zhang, Fang Chen, Nan Chen, Chenghong Huang

Abstract read

In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao LiSchool of Chemistry and Chemical Engineering, Chongiqng University of Science and Technology, Chongqing 401331, China.

Lin ZhangSchool of Chemistry and Chemical Engineering, Chongiqng University of Science and Technology, Chongqing 401331, China.

You LongSchool of Chemistry and Chemical Engineering, Chongiqng University of Science and Technology, Chongqing 401331, China.

Chao ShenSchool of Chemistry and Chemical Engineering, Chongiqng University of Science and Technology, Chongqing 401331, China.

Song ZhangSchool of Chemistry and Chemical Engineering, Chongiqng University of Science and Technology, Chongqing 401331, China.

Fang ChenChongqing Key Laboratory of Digitalization in Pharmaceutical Processes, Chongiqng University of Science and Technology, Chongqing 401331, China.

Nan ChenChongqing Key Laboratory of Digitalization in Pharmaceutical Processes, Chongiqng University of Science and Technology, Chongqing 401331, China.

Chenghong HuangSchool of Chemistry and Chemical Engineering, Chongiqng University of Science and Technology, Chongqing 401331, China.

Funding

Basic Research and Frontier Exploration Program 2022TFII-OFX0218

6 · The paper itself

Abstract

Paclitaxel is a first-line anticancer drug, but its low water solubility impedes bioavailability. The purpose of this study is to estalish a delivery strategy via carboxymethyl chitosan (CMCS)-encapsulated 6-deoxy-6-mercapto-β-cyclodextrins (dmβCDs)-modified concave cubic gold (CCGs) to achieve PTX release. CCGs were initially synthesized by the one-pot method and further modified by dmβCDs, the dmβCDs can effectively capture PTX molecules, followed by encapsulation with CMCS, and then prepare pH-responsive CMCS/dmβCDs/CCGs nanocarriers after lyophilization. Results indicated that desirable hexagonal CCGs with 50 ± 5 nm size can be obtained by adjusting H

Indexed as

6-deoxy-6-mercapto-β-cyclodextrincarboxymethyl chitosanconcave cubic goldpaclitaxel

Identifiers

PMID41893253

DOI10.3390/nano16060378

PMCPMC13029284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.