Evidence map›Paper›PMID 41893188›Full record

ArticleJournal of functional biomaterials2026

Influence of the Topography of Zirconium Treated with Laser Micropatterning on Periodontal Ligament Stem Cells: An In Vitro Study.

Ildefonso Serrano-Belmonte, Alba Rico-Molina, Juan Ignacio Rosales-Leal, Guillermo Lorite-Méndez, Miguel Ángel Rodríguez-Valverde, Clara Serna-Muñoz, Ascensión Martínez-Cánovas

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ildefonso Serrano-BelmonteSchool of Dentistry, Faculty of Medicine, Clínica Odontológica Universitaria, 2 Planta, Hospital Morales Meseguer, Avda. Marqués de los Vélez s/n, 30008 Murcia, Spain.ORCID 0000-0002-9623-1393
Alba Rico-MolinaSchool of Dentistry, Faculty of Medicine, Clínica Odontológica Universitaria, 2 Planta, Hospital Morales Meseguer, Avda. Marqués de los Vélez s/n, 30008 Murcia, Spain.
Juan Ignacio Rosales-LealFaculty of Dentistry, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-4575-4098
Guillermo Lorite-MéndezApplied Physics Department, School of Science, University of Granada, 18071 Granada, Spain.ORCID 0009-0005-7119-3414
Miguel Ángel Rodríguez-ValverdeApplied Physics Department, School of Science, University of Granada, 18071 Granada, Spain.ORCID 0000-0003-4361-6721
Clara Serna-MuñozSchool of Dentistry, Faculty of Medicine, Clínica Odontológica Universitaria, 2 Planta, Hospital Morales Meseguer, Avda. Marqués de los Vélez s/n, 30008 Murcia, Spain.
Ascensión Martínez-CánovasSchool of Dentistry, Faculty of Medicine, Clínica Odontológica Universitaria, 2 Planta, Hospital Morales Meseguer, Avda. Marqués de los Vélez s/n, 30008 Murcia, Spain.

Funding

Ministerio de Ciencia, Innovación y Universidades PID2020.116082GB.I00Universidad de Granada Project C-CTS-305-UGR23
6 · The paper itself

Abstract

Zirconium is a widely used material in the field of dentistry, employed for implants and their components as well as for the creation of crowns and veneers. Given that its biocompatibility has been studied and demonstrated in various fields of application, it is necessary to analyze how surface modification of this material influences its properties. The purpose of this study was to analyze the biocompatibility, initial adhesion (48 h), and morphology of periodontal ligament stem cells (PDLSCs) seeded on different zirconium surfaces treated with laser micropatterning, as well as plastic coverslips as a control. The Neubauer chamber was used to count the cells adhered to each of the sets, and confocal and scanning electron microscopy were employed to examine the adhesion and morphology of periodontal ligament stem cells on each of the zirconium surfaces studied. Results: Statistically significant differences were found in terms of primary cell adhesion, with sets 3 (grid topography) and 4 (channel topography) showing the most favorable characteristics for fibroblast adhesion. It was concluded that regular and moderately rough surfaces promoted better cell proliferation and development.

Indexed as

implant abutmentinitial adhesionlaser micropatterningperiodontal ligament stem cellszirconium

Identifiers

PMID41893188
PMCPMC13028466

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.