ArticleJournal of functional biomaterials2026
Biomechanical Evaluation of CAD/CAM Inlay Restorations Through Experimental Flexural Strength Testing and Finite Element Analysis.
Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
backgroundThis study aimed to investigate the biomechanical behavior of conservative inlay restorations fabricated from different CAD/CAM materials by combining experimental flexural strength testing with finite element analysis.
methodsFive CAD/CAM materials were evaluated: feldspathic ceramic (Cerec Blocs), leucite-reinforced ceramic (IPS Empress CAD), resin nano-ceramic (Lava Ultimate), polymer-infiltrated ceramic network (VITA Enamic), and lithium disilicate ceramic (IPS e.max CAD). Young's modulus and Poisson's ratio were experimentally determined using three-point bending and nanoindentation tests and used as inputs for 3D FEA. Von Mises (VM) stress distributions within the inlays were analyzed under simulated occlusal loading.
resultsMaximum VM stresses showed an inverse relationship with material elasticity. IPS e.max CAD exhibited the highest maximum VM stress (45.571 MPa), whereas the resin nano-ceramic showed the lowest (25.419 MPa). Despite higher stress concentrations in high-modulus ceramics, VM values for all materials remained well below their FS limits.
conclusionsAll materials demonstrated adequate mechanical stability under physiological loading. Lithium disilicate showed a comparatively larger margin between stress levels and flexural strength, while lower-modulus materials tended to promote greater stress transfer to supporting structures.
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