Neonatal Candidemia in Latin America: Trends, Resistance, and Prevention Strategies (2008-2025).

Fredi Giovanni Soto Guzmán, Pilar Rivas-Pinedo, Jose Millan Onate Gutierrez

Abstract readReview

In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fredi Giovanni Soto GuzmánDepartment of Microbiology, Faculty of Medicine, Universidad Nacional de Colombia, Bogotá 111321, Colombia.ORCID 0000-0002-6291-0902

Pilar Rivas-PinedoMedical and Diagnostic Mycology Group, Department of Microbiology, Faculty of Medicine, Universidad Nacional de Colombia, Bogotá 111321, Colombia.ORCID 0000-0002-6034-3182

Jose Millan Onate GutierrezOne Health Research Group for Infectious Diseases, Keralty, Department of Internal Medicine, Clínica Colsanitas S.A., Clínica Sebastián de Belalcázar, Cali 760045, Colombia.ORCID 0000-0002-6180-792X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candidemia and invasive candidiasis remain significant causes of late-onset sepsis and mortality in very-low-birth-weight infants, especially in low- and middle-income countries. This narrative review synthesizes studies published between 2008 and 2025 in Latin America, addressing epidemiology, species distribution, antifungal susceptibility patterns, risk factors, therapeutic approaches, and clinical outcomes, with international comparisons. Accordingly, we present a qualitative narrative synthesis (see Methods) rather than a formal year-over-year temporal trend quantification. Globally, five species predominate, namely

Indexed as

antifungal resistanceantifungal stewardshipCandida parapsilosis sensu lato (s.I.)Candidozyma aurisfluconazole prophylaxisinvasive candidiasisLatin Americaneonatal candidemianeonatal intensive care unitspremature infant

Identifiers

PMID41893162

DOI10.3390/jof12030230

PMCPMC13027495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.