ReviewNeurology international2026
Genetic Architecture of Cognitive Resilience in Alzheimer's Disease: Mechanisms, Pathways, and Therapeutic Implications.
Gabriel Burdman, Juliet Akkaoui, Natalia Colon, Andres Perez, Madepalli K Lakshmana
Abstract readReview
In one paragraphReview in Neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
5 authors.
Gabriel BurdmanDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Juliet AkkaouiDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0003-1716-4928 Natalia ColonDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Andres PerezDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Madepalli K LakshmanaDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Funding
Targeting Inflammasome with stable endocannabinoid ligand AMG315. CRISPR/Cas9 and nanotechnology study in the context of HIV and cannabinoidR01DA052271 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI LAKSHMANA, MADEPALLI KRISHNAPPA, MAKRIYANNIS, ALEXANDROS · 2020 to 2024
$2.2MEffect of small molecule activator of autophagy on insulin signaling, senescence, and neuropathology in mouse models of Alzheimer's diseaseR61AG086971 · NIA · FLORIDA INTERNATIONAL UNIVERSITY · PI Madepalli Krishnappa Lakshmana, Adel Nefzi · 2025 to 2026
$959kThe potential benefits of autophagy activator TFEB in opioid use disorder in miceR21DA060111 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI LAKSHMANA, MADEPALLI KRISHNAPPA · 2024 to 2024
$406kNational Institute of Health (NIH) USA 5R01DA052271, 1R21DA060111, 1R61AG086971NIA NIH HHS R61 AG086971NIDA NIH HHS R01 DA052271NIDA NIH HHS R21 DA060111
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
Alzheimer’s diseaseamyloid-βAPOEclinicopathologic dissociationcognitive resiliencegenetic modifierslipid metabolismmicrogliasynaptic integritytau
Identifiers
PMID41893052
PMCPMC13029736
What OpenQuestion holds
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