From Sea to Sight: Fucoidan Protects Against Oxidative Damage in Porcine Retina Organ Culture.

Leonie Deppe, Philipp Dörschmann, H Burkhard Dick, Alexa Klettner, Stephanie C Joachim

Abstract read

In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leonie DeppeExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.

Philipp DörschmannDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.ORCID 0009-0001-7062-9918

H Burkhard DickExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.

Alexa KlettnerDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.ORCID 0000-0002-2709-1059

Stephanie C JoachimExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.ORCID 0000-0001-7056-0829

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degeneration of retinal ganglion cells (RGCs) is a hallmark of glaucoma. As RGCs are vulnerable to oxidative imbalance, anti-oxidative strategies are of significant interest as novel therapeutic targets. Fucoidans, bioactive compounds derived from algae, are known to be anti-oxidative. Hence, we investigated if fucoidans have protective effects in a retina organ culture model. Porcine explants were pre-treated with fucoidan (

Indexed as

AntioxidantsOxidative StressPolysaccharidesRetinaRetinal Ganglion CellsAnimalsApoptosisGlaucomaHydrogen PeroxideOrgan Culture TechniquesSwineAntioxidantsfucoidanHydrogen PeroxidePolysaccharidesfucoidanglaucomaneuroprotectionoxidative stressporcine organ culture model

Identifiers

PMID41892947

DOI10.3390/md24030088

PMCPMC13028070

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.