Evidence map›Paper›PMID 41892872›Full record

SynthesisMedical sciences (Basel, Switzerland)2026

Histopathological Changes Following Bromelain-Based Enzymatic Debridement (NexoBrid

Stefana Avadanei-Luca, Dan-Cristian Moraru, Andra-Irina Bulgaru-Iliescu, Raluca Tatar, Iulia Nacea, Alexandru Hristo Amarandei, Mihai-Codrin Constantinescu, Mihaela Pertea

Abstract readSystematic Review
In one paragraph

Synthesis in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stefana Avadanei-LucaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-9192-7607
Dan-Cristian MoraruGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Andra-Irina Bulgaru-IliescuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0005-0145-7269
Raluca TatarGrigore Alexandrescu Clinica Emergency Hospital for Children Bucharest, 010621 Bucharest, Romania.ORCID 0000-0002-4606-4064
Iulia NaceaGrigore Alexandrescu Clinica Emergency Hospital for Children Bucharest, 010621 Bucharest, Romania.ORCID 0009-0008-9760-5896
Alexandru Hristo AmarandeiGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Mihai-Codrin ConstantinescuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Mihaela PerteaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-5308-7192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BromelainsBurnsDebridementAnimalsHumansRatsWound HealingBromelainsbromelainburnsenzymatic debridementhistologyhistopathologyNexoBrid®wound healing

Identifiers

PMID41892872
PMCPMC13028588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.