ArticleMedical sciences (Basel, Switzerland)2026
VMAT for Head and Neck Cancer: What Is the Impact of the Optimization Parameters on the Treatment Plan Quality?
Article in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo evaluate the effectiveness of different optimization parameters on radiotherapy plan quality for seventeen head and neck cancer patients.
methodsVolumetric Modulated Arc Therapy with Simultaneous Integrated Boost (VMAT-SIB) plans, involving up to three tumors, were generated. For each participant, a reference plan (Plan_Ref) was created using dual-arc with 180 control points, 20° gantry-angle increment and 1 cm minimum segment width. Modified plans were developed with dose constraints and optimization settings constant by changing to single-arc, 150 and 200 control points, 0.5 cm minimum segment width, and 30° and 40° gantry-angle increments. These plans were referred to as Plan_Arc1, Plan_CP150, Plan_CP200, Plan_SW0.5, Plan_Inc30, and Plan_Inc40, respectively. D
resultsAverage D
conclusionsThe VMAT plan quality is strongly affected by the minimum segment width whereas no differences were observed with the modification of the number of control points.
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