Evidence map›Paper›PMID 41892807›Full record

Observational studyPhysical therapy2026

Early mobilization in patients with aneurysmal subarachnoid hemorrhage: a prospective observational study.

Sabrina Hernandez, Claire Tipping, Adam M Deane, Michael Wei, Wendy Bower, Alexios Adamides, Anais Charles-Nelson, Peter Thomas, Jonathan Tomkins, Jane Larkin and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Physical therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sabrina HernandezAllied Health Department, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.ORCID 0000-0002-4151-7677
Claire TippingPhysiotherapy Department, The Alfred Hospital, Melbourne, VIC 3004, Australia.ORCID 0000-0003-2543-1467
Adam M DeaneDepartment of Intensive Care, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.ORCID 0000-0002-7620-5577
Michael WeiDepartment of Neurosurgery, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.ORCID 0000-0003-3500-5146
Wendy BowerAllied Health Department, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.ORCID 0000-0003-2029-4731
Alexios AdamidesDepartment of Neurosurgery, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.ORCID 0009-0009-8038-9485
Anais Charles-NelsonAustralian and New Zealand Intensive Care-Research Center, School of Public Health and Preventive Medicine, Monash University, Parkville, VIC 3050, Australia.ORCID 0000-0001-6437-7059
Peter ThomasThe Royal Brisbane and Women's Hospital, Herston, QLD 4029, Australia.ORCID 0000-0003-3160-8257
Jonathan TomkinsAllied Health Department, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.ORCID 0009-0007-0427-4737
Jane LarkinAllied Health Department, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.ORCID 0009-0004-1991-4360
Carol L HodgsonAustralian and New Zealand Intensive Care-Research Center, School of Public Health and Preventive Medicine, Monash University, Parkville, VIC 3050, Australia.ORCID 0000-0001-9002-2075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importancePatients with aneurysmal subarachnoid hemorrhage (aSAH) represent a cohort with limited evidence to guide mobilization practices.

objectiveThe objective was to describe acute mobilization practices, outcomes, and barriers to mobilization in patients following aSAH.

designThe design of the study was a single-center prospective, observational study.

settingThis study was conducted in the acute ward and intensive care unit of a tertiary neurosurgical referral center.

participantsParticipants were adult (≥18 years) patients post-aSAH with secured aneurysms. EXPOSURE: Mobilization practices were delivered during physical therapist sessions up to 14 days post-aneurysm repair. MAIN OUTCOMES AND MEASURES: Severity was classified using the World Federation of Neurological Surgeons scale, dichotomizing into "good" (Grade I to II) and "poor" (Grade III to V) clinical status. Mobilization outcomes were measured using the Mobility Scale for Acute Stroke (MSAS), with independent walking assessed.

resultsA total of 102 patients participated with 69 (67.6%) classified as "good" grade and 90 (88.2%) of patients mobilized within the first 14 days. Data were collected from 603 planned mobilization sessions, with barriers to mobilization encountered in 193 (32.0%) of these sessions, primarily due to neurological instability (n = 80, 41.5%) and hemodynamic instability (n = 43, 22.3%). Overall, the highest median MSAS score achieved was 32 (IQR = 10 to 36). By 2 weeks, 65.2% of patients with a "good" clinical status walked independently versus 12.9% in the "poor" group.

conclusionsWhile most patients mobilized, physiological instability commonly prevented mobilization activities. Independent walking by 2 weeks was significantly more common in patients with "good" clinical status. These findings underline the importance of careful screening and monitoring during mobilization in the acute period. RELEVANCE: This study underscores the need for further research into optimal mobilization strategies for improving outcomes in patients with aSAH.

Indexed as

Early AmbulationSubarachnoid HemorrhageAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesTreatment Outcomeaneurysmal subarachnoid haemorrhageEarly mobilizationindependent walkingmobilization barriers

Identifiers

PMID41892807
PMCPMC13134040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.