Evidence map›Paper›PMID 41892693›Full record

ArticleJournal of cardiovascular development and disease2026

Reproducibility of Echocardiographic Measurements of Right Ventricular Function: Comparison Between TAPSE and TDI S'.

Gianluca Pagnoni, Dilia Giuggioli, Susan Darroudi, Marco de Pinto, Arianna Maini, Amelia Spinella, Gilda Sandri, Marcello Pinti, Daniela Aschieri, Alessio Baccarani and 3 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Utilizing bedside VExUS and the S-prime velocity for real-time assessment of venous congestion on right ventricular function in heart failure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Chemotherapy-Induced Right Ventricular Dysfunction.Medicina (Kaunas, Lithuania) · 2026
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gianluca PagnoniCardiology Unit of Emergency Department, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0009-0008-7067-279X
Dilia GiuggioliDepartment of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, Italy.ORCID 0000-0002-0041-3695
Susan DarroudiDepartment of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, Italy.
Marco de PintoRheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0002-0947-8663
Arianna MainiCardiology Division, Department of Biomedical Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, Italy.
Amelia SpinellaDepartment of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, Italy.
Gilda SandriRheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0003-0454-1093
Marcello PintiNational Institute for Cardiovascular Research (INRC), Via Irnerio 48, 40126 Bologna, Italy.ORCID 0000-0001-9118-1262
Daniela AschieriCardiology Unit of Emergency Department, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0000-0002-1577-5402
Alessio BaccaraniDivision of Plastic and Reconstructive Surgery, Department of Medical and Surgical Sciences, Modena Policlinico Hospital, University of Modena and Reggio Emilia, 41124 Modena, Italy.
Anna Vittoria MattioliNational Institute for Cardiovascular Research (INRC), Via Irnerio 48, 40126 Bologna, Italy.ORCID 0000-0003-1487-9530
Francesco FedeleNational Institute for Cardiovascular Research (INRC), Via Irnerio 48, 40126 Bologna, Italy.
Francesca CoppiDepartment of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, Italy.ORCID 0000-0001-7715-6941

Funding

National Institute for Cardiovascular Research, Bologna, Italy Project PE_00000019
6 · The paper itself

Abstract

(1) Background: Assessment of right ventricular (RV) function has become increasingly important in echocardiography due to its prognostic significance in cardiac and systemic diseases. (2) Objectives: Tricuspid Annular Plane Systolic Excursion (TAPSE) and Tissue Doppler Imaging (TDI S') are commonly used methods to assess RV function. The aim of this study was to compare the reproducibility of TAPSE and TDI S' among experienced operators. (3) Methods: A study was conducted on 100 consecutive patients with systemic sclerosis undergoing echocardiography evaluation screening for pulmonary hypertension. Standardized echocardiography images were acquired using a Philips EPIQ system (Philips Healthcare, Amsterdam, The Netherlands), measuring TAPSE and TDI S'. Five operators independently analyzed the images, with each blinded to the results. Exclusion criteria included pathological TAPSE or TDI S' values, as well as indirect echocardiography signs of pulmonary hypertension. (4) Results: The study's results indicate that there was superior inter-operator agreement for TDI S' (ICC = 0.891) compared to TAPSE (ICC = 0.47). The mean TAPSE measurements ranged from 23.49 mm to 23.99 mm, while TDI S' values ranged from 12.16 cm/s to 12.35 cm/s, with TDI S' showing narrower confidence intervals. (5) Conclusions: Echocardiographic assessment of right ventricular (RV) function is crucial in clinical practice. Tissue Doppler imaging-derived systolic velocity (TDI S') demonstrated superior reproducibility compared to tricuspid annular plane systolic excursion (TAPSE) in evaluating RV function. This enhanced reproducibility supports the routine incorporation of TDI S' as a highly reproducible parameter within a multiparametric assessment framework.

Indexed as

echocardiographyreproducibilityTAPSETDI

Identifiers

PMID41892693
PMCPMC13026364

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.