Evidence map›Paper›PMID 41892529›Full record

ReviewGels (Basel, Switzerland)2026

Scoping Review of the Biomedical Investigations of Cellulose Nanocrystal-Based Hydrogels: A Critical Analysis of Current Evidence, Research Gaps and Future Perspectives.

Dinuki M Seneviratne, Eliza J Whiteside, Louisa C E Windus, Paulomi Polly Burey, Raelene Ward, Pratheep K Annamalai

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dinuki M SeneviratneSchool of Health and Medical Sciences, University of Southern Queensland, Toowoomba, QLD 4350, Australia.ORCID 0000-0001-7867-3078
Eliza J WhitesideSchool of Health and Medical Sciences, University of Southern Queensland, Toowoomba, QLD 4350, Australia.ORCID 0000-0001-9710-7987
Louisa C E WindusSchool of Health and Medical Sciences, University of Southern Queensland, Toowoomba, QLD 4350, Australia.ORCID 0000-0002-7186-459X
Paulomi Polly BureySchool of Science, Engineering and Digital Technologies, Centre for Future Materials, University of Southern Queensland, Toowoomba, QLD 4350, Australia.ORCID 0000-0001-9248-2307
Raelene WardFirst Nations Engagement, Institute for Resilient Regions, University of Southern Queensland, Toowoomba, QLD 4350, Australia.ORCID 0000-0002-6248-7921
Pratheep K AnnamalaiSchool of Science, Engineering and Digital Technologies, Centre for Future Materials, University of Southern Queensland, Toowoomba, QLD 4350, Australia.ORCID 0000-0002-7284-0813

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogel-based products are used in many areas of biomedicine and healthcare. Recently, the incorporation of cellulose nanocrystals (CNC), a renewable and functional nanomaterial, into hydrogels has enhanced their functionality, particularly by imparting mechanical strength and structural integrity. This scoping review aims to appraise the types of biomedical models and assays that have been utilised to investigate the effects of CNC incorporation into hydrogels in tissue engineering, wound healing, medical implantation and drug delivery applications, and reports on the rationale for including these models and assays. A structured literature search was undertaken in major scientific databases (PubMed Central, PubMed, BioMed Central, ScienceDirect, Wiley and EBSCOhost), focusing on identifying primary research published between 2016 and 2024. From this process, fifteen studies providing biomedical analyses met the inclusion criteria. Most of these investigations employed in vitro cell-line models (

Indexed as

animal modelsbiomedical modelscell linescellulose nanocrystalshealthcare applicationshydrogel

Identifiers

PMID41892529
PMCPMC13025112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.