Evidence map›Paper›PMID 41892498›Full record

ArticleClinics and practice2026

Performance Validation of ORTHOSEG, a Novel Artificial Intelligence Tool for the Segmentation of Orthopantomographs and Intra-Oral X-Rays.

Giuseppe Cota, Gaetano Scaramozzino, Marco Chiesa, Lelio Gennaro, Maurizio Pascadopoli, Andrea Scribante, Marco Colombo

Abstract read
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Article in Clinics and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Giuseppe CotaScaramozzino Dental Practice, 45020 Villanova del Ghebbo, RO, Italy.
Gaetano ScaramozzinoScaramozzino Dental Practice, 45020 Villanova del Ghebbo, RO, Italy.
Marco ChiesaSection of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, PV, Italy.
Lelio GennaroSection of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, PV, Italy.
Maurizio PascadopoliSection of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, PV, Italy.ORCID 0000-0003-1690-4904
Andrea ScribanteSection of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, PV, Italy.ORCID 0000-0002-2760-0124
Marco ColomboSection of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, PV, Italy.ORCID 0000-0001-8820-5489

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDental radiographs are essential for diagnosis and treatment planning in modern dentistry. However, their manual interpretation is time-consuming and subject to variability, highlighting the need for automated tools to improve efficiency and consistency. This study aims to validate ORTHOSEG, a deep learning-based system designed to automate the segmentation of anatomical, pathological, and non-pathological elements in radiographs, including orthopantomograms, bitewings, and periapical images.

methodsORTHOSEG's performance was evaluated using a rigorously curated dataset of 150 dental radiographs, including 50 orthopantomograms, 50 bitewings, and 50 periapical images, with manual annotations by expert clinicians serving as the ground truth. The system's segmentation performance was assessed using standard evaluation metrics, including mean Dice Similarity Coefficient (

resultsThe system achieved high accuracy, with

conclusionsORTHOSEG demonstrates efficiency suitable for integration into routine workflows. This study confirms ORTHOSEG's reliability and potential to improve diagnostic workflows, offering clinicians a valuable tool for faster and more detailed radiograph analysis. Future research will focus on extending validation across diverse clinical scenarios to ensure broader applicability. However, this study has limitations, including the use of a dataset derived from a European population and the absence of usability and clinical workflow evaluation, which should be addressed in future studies.

Indexed as

automated segmentationbitewing radiographycomputer-aided diagnosisconvolutional neural networkdeep learningdental radiographyimage segmentationorthopantomographyperiapical radiography

Identifiers

PMID41892498
PMCPMC13024870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.