Evidence map›Paper›PMID 41892478›Full record

ReviewAntibiotics (Basel, Switzerland)2026

Bacteriophage Therapy Against

Giuseppe Guido Maria Scarlata, Andrej Belančić, Davor Štimac, Almir Fajkić, Tomislav Meštrović, Ludovico Abenavoli

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giuseppe Guido Maria ScarlataDepartment of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy.ORCID 0000-0002-7084-8264
Andrej BelančićDepartment of Basic and Clinical Pharmacology with Toxicology, Faculty of Medicine, University of Rijeka, Braće Branchetta 20, 51000 Rijeka, Croatia.ORCID 0000-0001-7848-6600
Davor ŠtimacDepartment of Gastroenterology, Clinical Hospital Centre Rijeka, 51000 Rijeka, Croatia.ORCID 0009-0006-0015-4183
Almir FajkićDepartment of Pathophysiology, Faculty of Medicine, University of Sarajevo, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-3722-9701
Tomislav MeštrovićUniversity Centre Varaždin, University North, 42000 Varaždin, Croatia.ORCID 0000-0002-8751-8149
Ludovico AbenavoliDepartment of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy.ORCID 0000-0002-5922-1524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shigellosis remains a significant global cause of infectious colitis, increasingly complicated by multidrug-resistant strains and the microbiota-disrupting effects of broad-spectrum antibiotics. Although conventional antimicrobial therapy can reduce symptom duration and bacterial shedding, it also contributes to gut dysbiosis, loss of colonization resistance, and further selection for antimicrobial resistance. These challenges have renewed interest in precision antimicrobial strategies, particularly bacteriophage therapy, which provides strain-level specificity and preserves the gut microbiota. This narrative review evaluates the biological rationale, preclinical and early clinical evidence, safety considerations, and translational challenges associated with bacteriophage therapy targeting

Indexed as

infectionmanagementprecision medicinetreatment

Identifiers

PMID41892478
PMCPMC13024384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.