Evidence map›Paper›PMID 41892469›Full record

ArticleAntibiotics (Basel, Switzerland)2026

Antibiotic Resistance Awareness and Prescribing Behavior Among General Practitioners in Kazakhstan, Kyrgyzstan, Uzbekistan, and Tajikistan.

Yuliya Semenova, Kamila Akhmetova, Shakhnoza Rakhmatullaeva, Makhbuba Muminova, Dilafruz Fakhriddinova, Kenesh Dzhusupov, Asel Kanymetova, Damira Ashyralieva, Mukhabbat Saidova, Shakhlo Yakubova and 2 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuliya SemenovaDepartment of Surgery, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0003-1324-7806
Kamila AkhmetovaDepartment of Public Health and Management, Astana Medical University, Astana 010000, Kazakhstan.
Shakhnoza RakhmatullaevaDepartment of Infectious Diseases, Tashkent State Medical University, Tashkent 100109, Uzbekistan.
Makhbuba MuminovaDepartment of Infectious Diseases, Tashkent State Medical University, Tashkent 100109, Uzbekistan.
Dilafruz FakhriddinovaDepartment of Infectious Diseases, Tashkent State Medical University, Tashkent 100109, Uzbekistan.
Kenesh DzhusupovDepartment of Public Health, International Higher School of Medicine, Bishkek 720054, Kyrgyzstan.ORCID 0000-0002-2213-1373
Asel KanymetovaScientific and Practical Center for Infection Control at the National Institute of Public Health, Bishkek 720014, Kyrgyzstan.
Damira AshyralievaScientific and Practical Center for Infection Control at the National Institute of Public Health, Bishkek 720014, Kyrgyzstan.
Mukhabbat SaidovaDepartment of Pharmaceutical Chemistry and Pharmacy Management and Economics, Tajik National University, Dushanbe 734025, Tajikistan.
Shakhlo YakubovaDepartment of Pharmaceutical Chemistry and Pharmacy Management and Economics, Tajik National University, Dushanbe 734025, Tajikistan.
Lyudmila PivinaDepartment of Emergency Medicine, Semey Medical University, Semey 071407, Kazakhstan.ORCID 0000-0002-8035-4866
Zaituna KhismetovaDepartment of Public Health, Semey Medical University, Semey 071407, Kazakhstan.

Funding

Nazarbayev University OPCRP2024008 "Evidence-based practice and policy to improve antibiotic stewardship and reduce antimicrobial resistance in Central Asia."
6 · The paper itself

Abstract

BACKGROUND/

objectivesDespite a wide range of international studies examining antibiotic prescribing practices among physicians, research from Central Asia remains scarce. To address this gap, the present study aimed to investigate antibiotic resistance awareness and prescribing practices among general practitioners (GPs) in Kazakhstan, Kyrgyzstan, Uzbekistan, and Tajikistan.

methodsThe online questionnaire was completed by 1231 GPs, including 469 from Kazakhstan, 274 from Kyrgyzstan, 369 from Uzbekistan, and 119 from Tajikistan.

resultsMost physicians (71.1%) acknowledged that their antibiotic prescribing behavior influences the development of antibiotic resistance in their regions. More than half reported discussing antibiotic resistance with their patients often or very often. However, the strategy of delayed antibiotic prescribing was unknown to 27.1% of GPs. Factors associated with good knowledge of indications for antibiotic prescribing included female sex, older age, working in Uzbekistan, practicing in urban areas, seeing 20 or more patients per day, and use of practice guidelines. Clinical practice guidelines were the most frequently reported source of current information on antibiotic therapy and resistance (20.4%), followed by continuing professional education (15.9%) and textbooks (14.1%). The vast majority of GPs (94.4%) indicated a need for additional information resources to support more rational antibiotic prescribing. The most commonly cited needs were higher-quality clinical practice guidelines (22.5%) and better access to existing guidelines (17.7%).

conclusionsThese findings suggest that, despite generally high awareness of antibiotic resistance, important knowledge gaps remain among GPs in Central Asia. Strengthening access to clinical guidelines and continuing professional education may support more rational antibiotic prescribing.

Indexed as

antibiotic prescribing behaviorantimicrobial resistance awarenessCentral Asiageneral practitioners

Identifiers

PMID41892469
PMCPMC13024538

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Registered trials

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