Evidence map›Paper›PMID 41892461›Full record

ArticleAntibiotics (Basel, Switzerland)2026

Genetic Characterization and Biofilm-Forming Capacity of Bacterial Population Isolated from Conjunctival Samples.

Adela Voinescu, Silvia-Ioana Musuroi, Monica Licker, Delia Muntean, Florin-George Horhat, Luminita Mirela Baditoiu, Oana Izmendi, Andrei Cosnita, Mihnea Munteanu, Mihai Poenaru-Sava and 4 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Adela VoinescuDoctoral School, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Silvia-Ioana MusuroiDoctoral School, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Monica LickerMultidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.ORCID 0000-0002-9245-5883
Delia MunteanMultidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.ORCID 0000-0001-9100-4530
Florin-George HorhatMultidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.ORCID 0000-0001-6133-0204
Luminita Mirela BaditoiuMultidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.ORCID 0000-0003-1572-1196
Oana IzmendiDoctoral School, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-7644-8109
Andrei CosnitaDepartment IX, Surgery and Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300002 Timisoara, Romania.ORCID 0009-0005-6141-0198
Mihnea MunteanuDepartment IX, Surgery and Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300002 Timisoara, Romania.ORCID 0000-0001-9526-2211
Mihai Poenaru-SavaDepartment IX, Surgery and Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300002 Timisoara, Romania.ORCID 0009-0000-0502-9548
Valentin OrdodiCenter of Immuno-Physiology and Biotechnologies, Department of Functional Sciences, "Victor Babes" University of Medicine and Pharmacy, 300173 Timisoara, Romania.
Petrinela CeachirDoctoral School, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Tudor Rareș OlariuDiscipline of Parasitology, Department of Infectious Diseases, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-1094-3729
Corina MusuroiMultidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesBacterial conjunctivitis is a common ocular infection requiring prompt treatment, particularly in vulnerable patients, and may influence perioperative outcomes. This study aimed to characterize conjunctival bacterial isolates phenotypically and genotypically, to evaluate their biofilm-forming capacity, and to investigate the relationship between resistance gene carriage, resistance phenotypes, and biofilm-associated antimicrobial resistance (AMR).

methodsA prospective, single-center, cross-sectional study was conducted on bacterial isolates from conjunctival samples of patients examined in an ophthalmology department. Antimicrobial susceptibility testing (AST) was performed to determine the minimum inhibitory concentrations (MICs). Resistance genes were detected by quantitative PCR. Biofilm-forming capacity was assessed using the microtiter plate assay, and biofilm susceptibility to amikacin (AK) and levofloxacin (LEV) was evaluated using a biofilm susceptibility assay.

resultsA total of 78 isolates were analyzed; Gram-positive cocci prevailed (GPC, 84.6%), being significantly more frequent than Gram-negative bacilli (GNB,

conclusionsThe prevalence of multidrug-resistant conjunctival isolates and their biofilm-forming capacity highlights the clinical importance of biofilm-related resistance and support integrating AMR profiling with biofilm assessment to optimize empirical therapy in bacterial conjunctivitis.

Indexed as

bacterial conjunctivitisbiofilmgenotypicphenotypicStaphylococcus aureusStaphylococcus epidermidis

Identifiers

PMID41892461
PMCPMC13024031

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.