Evidence map›Paper›PMID 41892207›Full record

ArticleCurrent oncology (Toronto, Ont.)2026

Hepatitis B Virus Infection Is Associated with a Higher Risk of Liver Metastasis in Gastric Cancer.

Songting Zhu, Mengmeng Jiang, Yanyan Chen, Yongfeng Ding, Haiyong Wang, Lisong Teng

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Songting ZhuDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Mengmeng JiangDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.ORCID 0009-0004-0701-3602
Yanyan ChenDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Yongfeng DingDepartment of Medical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Haiyong WangDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Lisong TengDepartment of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.ORCID 0000-0001-6470-9017

Funding

National Natural Science Foundation of China No. 82403515
6 · The paper itself

Abstract

backgroundHepatitis B virus infection has been linked to liver cancer and may influence metastasis in other malignancies, but its role in gastric cancer liver metastasis (GCLM) is unclear.

methodsWe retrospectively analyzed 776 gastric cancer patients with HBV testing. HBV infection was defined as HBsAg+ (chronic HBV, CHB) or HBsAg- with HBcAb/HBeAb+ (occult HBV, OHB). Among the 776 patients, 300 (38.6%) were classified as HBV+. The association between HBV infection and GCLM was evaluated, and propensity score matching (PSM) was performed to adjust for age and gender. Furthermore, the impact of HBV infection on overall survival (OS) was analyzed.

resultsGCLM occurred in 19.5% of patients. HBV+ patients had a higher GCLM prevalence than HBV- patients (25.3% vs. 15.8%;

conclusionHBV infection significantly increases the risk of liver metastasis in gastric cancer. Enhanced surveillance for liver metastasis is warranted in these patients.

Indexed as

Hepatitis BLiver NeoplasmsStomach NeoplasmsAgedFemaleHepatitis B virusHumansMaleMiddle AgedRetrospective StudiesRisk Factorsgastric cancerhepatitis B virusliver metastasisprognosis

Identifiers

PMID41892207
PMCPMC13025660

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