Evidence map›Paper›PMID 41892065›Full record

ReviewBiosensors2026

Microfluidic-Based Whole-Cell Biosensor Systems-Challenges and Future Applications.

Niklas Fante, Alexander Grünberger

Abstract readReview
In one paragraph

Review in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Niklas FanteMultiscale Bioengineering, Faculty of Technology Bielefeld University, Universitätsstraße 25, 33615 Bielefeld, Germany.ORCID 0009-0003-4423-5370
Alexander GrünbergerCenter for Biotechnology (CeBiTec), Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.ORCID 0000-0002-7564-4957

Funding

Bundesministerium für Forschung, Technologie und Raumfahrt 031B0826D
6 · The paper itself

Abstract

The integration of whole-cell biosensors in miniaturized measuring devices to exploit synergetic effects as small, rapid, cost-effective, sensitive, and highly specific platforms with point-of-care applicability was often discussed in recent years and many different setups have been presented to date. In many cases these setups were envisaged as powerful systems in their respective fields; however, the anticipated success often failed to materialize, and the systems remained a proof-of-concept. We elaborate on the hurdles and possible challenges that have to be overcome for the successful development and application of such systems. Further, we critically discuss and rank the impact of different challenges during system development, application, and commercialization. Finally, we point out possible future applications and conclude future perspectives for whole-cell biosensors integrated into microfluidic platforms.

Indexed as

Biosensing TechniquesMicrofluidic Analytical TechniquesMicrofluidicsbiohybrid systemsbiosensorcell-based biosensorimmobilizationin situ testingMEMSmicrobial biosensorminiaturizationpoint-of-careµTAS

Identifiers

PMID41892065
PMCPMC13024365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.