Evidence map›Paper›PMID 41892030›Full record

ReviewBiosensors2026

Surface Plasmon Resonance as a Tool in Antiviral Drug Discovery Research.

Katarzyna E Wegrzyn, John M Matsoukas

Abstract readReview
In one paragraph

Review in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katarzyna E WegrzynLaboratory of Molecular Biology, Intercollegiate Faculty of Biotechnology of the University of Gdansk and the Medical University of Gdansk, University of Gdansk, Abrahama 58, 80-307 Gdansk, Poland.ORCID 0000-0002-3743-8597
John M MatsoukasDepartment of Chemistry, University of Patras, 26504 Patras, Greece.ORCID 0000-0001-5554-2964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses are an indispensable part of the environment we live in. The occurrence of seasonal and pandemic infections underscores the urgent need to develop new antiviral drugs or repurpose existing ones. Among the methods used in research on new antiviral molecules, surface plasmon resonance (SPR) has a well-established position due to its diverse applications in interaction analysis. It can be used to investigate various molecules (proteins, nucleic acids, small-molecular drugs) in different configurations and in real time. Although it is a gold-standard method for biomolecular interaction analysis, it is not free of constraints. Here, we review research on SPR in antiviral drug discovery. We focus on experimental design and discuss the application of SPR to investigate key stages of viral infection and to characterize antiviral interactions. In addition, we address the main limitations and challenges associated with SPR measurements and consider strategies for adapting the technique to meet the specific needs of antiviral research.

Indexed as

Antiviral AgentsDrug DiscoverySurface Plasmon ResonanceBiosensing TechniquesHumansAntiviral Agentshost receptorimmobilizationsensor chipsmall-molecule inhibitorviral entry

Identifiers

PMID41892030
PMCPMC13023951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.