Evidence map›Paper›PMID 41891723›Full record

ArticleJournal of virology2026

Galectin-9 is a restrictor of infection with multiple enteroviruses.

Zichun Xiang, Guanying Wang, Wenjing Wang, Zhongqin Tian, Sunyuan Liu, Xia Xiao, Lili Ren, Zhuo Zhou, Xiaobo Lei, Jianwei Wang

Abstract read
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zichun Xiang *State Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.ORCID 0009-0007-3378-3311
Guanying Wang *State Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Wenjing Wang *State Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Zhongqin Tian *State Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Sunyuan LiuState Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Xia XiaoState Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Lili RenState Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.ORCID 0000-0002-6645-8183
Zhuo ZhouInstitute of Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, Jiangsu, People's Republic of China.ORCID 0000-0001-5862-9854
Xiaobo LeiState Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.ORCID 0000-0002-3455-6723
Jianwei WangState Key Laboratory of Respiratory Health and Multimorbidity, and Christophe Médrieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.ORCID 0000-0002-1116-4559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses (EVs), encompassing over 200 sero/genotypes, cause diseases ranging from mild illness to severe systemic infections. Galectin-9 (Gal-9) is an immunomodulatory lectin implicated in various viral infections, yet its role in EVs remains unexplored. Here, we identify Gal-9 as a novel host restriction factor against a broad spectrum of EVs, including EV-A71, EV-D68, and Coxsackievirus B2.

Indexed as

EnterovirusEnterovirus InfectionsGalectinsAnimalsCapsid ProteinsHumansMiceVirus ReplicationCapsid Proteinsgalectin 9, mouseGalectinsLGALS9 protein, humanenterovirusesgalectin 9VP2

Identifiers

PMID41891723
PMCPMC13098217

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.