Evidence map›Paper›PMID 41891684›Full record

ArticleThe breast journal2026

"Going Flat" in Nipple-Sparing Mastectomy-An Analysis of Patient-Reported Outcome Measurements of Preliminary 57 Procedures.

Jun Su, Yi-Yuan Lee, Wen-Bin Kao, Nurul Hidayah Abdul Rauf, Bing-Fang Hwang, Chiu-Ying Chen, Mee-Hoong See, Hung-Wen Lai

Abstract read
In one paragraph

Article in The breast journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jun SuDepartment of General Surgery, Tan Tock Seng Hospital, Singapore, ttsh.com.sg.ORCID 0000-0003-3751-1480
Yi-Yuan LeeDepartment of Public Health, China Medical University, Taichung, Taiwan, cmu.edu.cn.
Wen-Bin KaoDivision of Plastic and Reconstructive Surgery, Changhua Christian Hospital, Changhua, Taiwan, cch.org.tw.
Nurul Hidayah Abdul RaufDivision of Breast and Endocrine Surgery, Selayang Hospital, Selayang, Malaysia.
Bing-Fang HwangDepartment of Occupational Safety and Health, China Medical University, Taichung, Taiwan, cmu.edu.tw.ORCID 0000-0002-5951-9662
Chiu-Ying ChenDepartment of Public Health, China Medical University, Taichung, Taiwan, cmu.edu.cn.ORCID 0000-0001-8454-1151
Mee-Hoong SeeDepartment of Surgery, Faculty of Medicine, Breast Surgery Unit, Universiti Malaya, Kuala Lumpur, Malaysia, um.edu.my.ORCID 0000-0002-3966-3368
Hung-Wen LaiEndoscopic & Oncoplastic Breast Surgery Center, Changhua Christian Hospital, Changhua, Taiwan, cch.org.tw.ORCID 0000-0001-9541-2013

Funding

Changhua Christian Hospital 111-CCH-IRP-089Changhua Christian Hospital 114-CCH-ICO-153Changhua Christian Hospital 114-CCH-IRP105
6 · The paper itself

Abstract

backgroundNipple-sparing mastectomy (NSM) with immediate breast reconstruction (IBR) has become an increasingly popular procedure offering satisfactory aesthetic outcomes with adequate oncologic safety. However, outcomes of NSM without IBR have been rarely evaluated. We aim to assess the clinical outcomes of NSM in patients refusing IBR with a focus on patient-reported outcome measurements.

methodsThis retrospective study enrolled female breast cancer patients who underwent NSM but refused IBR from February 2010 to April 2022 in a single institution. Clinical outcomes and patient-reported aesthetic results were evaluated and analyzed.

resultsDuring the study period, there were 57 cases of primary breast cancer patients who underwent NSM but refused IBR. The mean operative duration was 186.6 min, and median length of hospital stay was 4 days. Median intraoperative blood loss was 30 mL with the median resected specimen weight at 360.5 g. There was no incidence of margin involvement in this study. The complication rate was 12.3% with all of them being minor complications with Clavien-Dindo I and II scores. Locoregional recurrence and distant metastasis during the study period were 5.3% and 1.8%, respectively, with a mean follow-up period of 64.4 months. There was no mortality during the study duration. Aesthetic outcomes assessed via the BREAST-Q questionnaire were satisfactory with mean scores ranging between 35.1 and 68.4.

conclusionThis study concludes that NSM in patients refusing IBR is an alternative compared to conventional mastectomy with acceptable aesthetic outcomes. These findings underscore the importance of individualized patient choices in breast cancer treatment.

Indexed as

Breast NeoplasmsMammaplastyMastectomy, SubcutaneousNipplesPatient Reported Outcome MeasuresAdultAgedFemaleHumansMastectomyMiddle AgedOrgan Sparing TreatmentsRetrospective Studiesbreast cancergoing flatimmediate breast reconstructionnipple-sparing mastectomy (NSM)patient-reported outcome

Identifiers

PMID41891684
PMCPMC13140869

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.