Evidence map›Paper›PMID 41891367›Full record

ReviewACS applied materials & interfaces2026

Janus Synapses as Modular Neurointerfaces.

Wonkyung Cho, Minji Jung, Taek Dong Chung

Abstract readReview
In one paragraph

Review in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wonkyung ChoDepartment of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-5358-5899
Minji JungDepartment of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0003-4239-8889
Taek Dong ChungDepartment of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-1092-8550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nervous system processes information by translating chemical signals into electrical and biochemical responses, ultimately driving biological adaptation and computation. Chemical synapses are the primary communication channels between neurons, operating with remarkable speed and precision to enable complex neural information processing. In this perspective, we focus on these native signaling principles and explore the potential of synaptic structures as neurointerface modules. Building on this view, we argue that electrodes can be engineered to function as complementary synaptic terminals, enabling neuron-device communication that directly leverages the chemical, electrical, and biological logic of neural systems. In particular, we discuss whether synaptic cell adhesion molecules can be harnessed as synaptogenic cues to redefine electrode surfaces as functional synaptic counterparts of neuronal terminals, and we examine the distinctive properties and emerging applications of such interfaces.

Indexed as

NeuronsSynapsesAnimalsElectrodesHumansbiohybrid neural interfacebrain−machine interfacehemisynapseneuron−electrode interfaceneurotransmitter-based communicationsynapse-inspired neurointerfacesynaptic cell adhesion molecule

Identifiers

PMID41891367
PMCPMC13067229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.