ArticleCancer medicine2026
Enhancing Quality of Life in Head and Neck Cancer: A Scoping Review on the Role of Physical Prehabilitation.
Article in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Integrative single-cell eQTL and multi-omics analyses reveal AIM1 and ANXA1 as immune-related hub genes and potential therapeutic targets in head and neck cancer.Frontiers in oncology · 2026Article
- The tongue may not move, but the voice will: preoperative AI voice cloning for identity preservation in major glossectomy - a prospective feasibility study.Frontiers in oncology · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
BACKGROUND/
aimHead and neck cancer presents a significant challenge for patients. Beyond the direct impact of the disease, chemotherapy and radiotherapy, while essential for cancer control, can further compromise patients' quality of life (QoL) and emotional well-being, while also introducing additional complications. These treatments may exacerbate existing cancer-related symptoms and contribute to malnutrition. This review aimed to identify and evaluate physical prehabilitation interventions implemented before or during radiotherapy/chemotherapy treatments to determine their impact on the QoL of patients with head and neck cancer.
methodsThis scoping review was structured according to the framework proposed by the Joanna Briggs Institute (JBI) and reported following the Preferred Reporting Items for Scoping Reviews (PRISMA-ScR) guidelines.
resultsEight studies were included, encompassing a total sample of 819 subjects (397 in experimental groups). The interventions identified included exercises and stretching to prevent mobility issues and trismus, home-based training programs with periodic supervision, comprehensive programs with supervised physiotherapy sessions, jaw mobility exercises, dysphagia therapy, oral exercises, and preventive rehabilitation. A positive association was found between prehabilitation interventions and improved QoL in patients. Customizing interventions based on patient characteristics and treatment modalities was shown to enhance the effectiveness of these programs.
conclusionsPrehabilitation interventions represent a holistic and functional approach to improving patient outcomes and QoL. Further research is needed to refine these approaches and optimize the overall QoL of head and neck cancer survivors.
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Registered trials
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