Evidence map›Paper›PMID 41891085›Full record

ReviewInternational journal of transgender health2026

Worldwide prevalence of anxiety in transgender persons: Systematic review with meta-analysis.

Davi Oliveira Teles, Raquel Alves de Oliveira, Manuela de Mendonça Figueirêdo Coelho, Ana Karina Bezerra Pinheiro, Fernando Lannes Fernandes

Abstract readReview
In one paragraph

Review in International journal of transgender health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Davi Oliveira TelesNursing Department, Federal University of Ceará, Fortaleza, Brazil.
Raquel Alves de OliveiraNursing Department, Federal University of Ceará, Fortaleza, Brazil.
Manuela de Mendonça Figueirêdo CoelhoNursing Department, Federal University of Ceará, Fortaleza, Brazil.
Ana Karina Bezerra PinheiroNursing Department, Federal University of Ceará, Fortaleza, Brazil.
Fernando Lannes FernandesSchool of Humanities, Social Sciences and Law, University of Dundee, Dundee, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This systematic review and meta-analysis estimate the global pooled prevalence of anxiety among transgender individuals. Methods: A comprehensive search was conducted in Scopus, Web of Science, Embase, EBSCOhost, VHL, PsycINFO, and PubMed. Observational studies reporting anxiety prevalence in transgender people were included. Meta-analytical methods were applied using a random-effects model to compute pooled prevalence estimates. Heterogeneity, publication bias, and subgroup analyses were assessed. Results: A total of 71 studies, comprising 73,565 transgender individuals from 23 countries, were included. The global pooled prevalence of anxiety was 43% (95% CI: 38-48%), with higher rates among non-binary individuals (59%) compared to transmasculine (44%) and transfeminine (37%) identities. Significant variability was observed across geographic regions, age groups, ethnicity/race of the samples, and assessment methods. Non-probabilistic sampling and self-reported measures were associated with higher prevalence estimates. Conclusion: Transgender individuals experience a disproportionately high prevalence of anxiety, with notable disparities by gender identity and region. Findings emphasize the need for targeted mental health interventions and inclusive healthcare policies. Standardized methodologies and broader geographical and ethnical representation in future research are essential to enhance global understanding and inform policy development.

Indexed as

Anxietymental healthmeta-analysissystematic reviewtransgender persons

Identifiers

PMID41891085
PMCPMC13015042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.