Evidence map›Paper›PMID 41891079›Full record

ReviewInternational journal of transgender health2026

The impact of tucking on fertility among transgender women: A systematic review.

Ethan Manafi, André R Belarmino, Jesse N Mills, Sriram V Eleswarapu, Gladys Y Ng

Abstract readReview
In one paragraph

Review in International journal of transgender health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ethan ManafiDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
André R BelarminoDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Jesse N MillsDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Sriram V EleswarapuDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Gladys Y NgDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Tucking involves maneuvering the testicles into the inguinal canal and compressing one's penis and scrotum posteriorly for a smoother pelvic area. A study based in Baltimore reports that 74.7% of transgender women engage in this practice. Objectives: Fertility preservation is a significant concern for many transgender women, however, the implications of tucking on fertility remain underexplored. This review aims to bridge this knowledge gap. Methods: Using PRIMSA guidelines, a systematic search across various databases was conducted to identify studies evaluating the impact of genital tucking on fertility. Keywords related to tucking, transgender identity, and fertility were utilized. Results: In total, 127 manuscripts were identified, of which 11 satisfied the inclusion and exclusion criteria. Four studies noted significant differences in semen parameters between cisgender men and transgender women prior to gender-affirming hormone therapy suggesting tucking as a potential factor. Two studies documented tucking prior to semen analysis but did not establish a definitive link between tucking and lower semen parameters in transgender women. One study, with a larger sample size of 113 transgender women, discovered an odds ratio of 7.95 between extensive tucking and low total motile sperm count. One year-long study on daily tucking reported a decline of up to 98% in total motile sperm count, and a complementary paper noted an increase in abnormal sperm morphology. Two case reports observed that after a 3-4 month cessation from tucking, semen parameters returned to normal. Conclusion: The review highlights the prevalence of tucking among transgender women and the negative impact on fertility it may have. Temporary cessation of tucking may improve semen parameters for fertility preservation. A harm reduction approach should be implemented to balance fertility aspirations with the management of gender dysphoria.

Indexed as

fertility preservationgenital tuckinginfertilitysemen analysistransgender persons

Identifiers

PMID41891079
PMCPMC13015063

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.