Evidence map›Paper›PMID 41890958›Full record

ArticleiScience2026

GAL and F2R as immune diagnostic biomarkers for fetal growth restriction.

Shiying Chen, Yumin Ke, Zhimei Zhou, Yajing Xie, Weihong Chen, Li Huang, Liying Sheng, Yueli Wang, Binbin Chen, Congmei Yang and 1 more

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shiying ChenDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Yumin KeDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Zhimei ZhouDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Yajing XieDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Weihong ChenDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Li HuangDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Liying ShengDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Yueli WangDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Binbin ChenDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Congmei YangDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Zhuna WuDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fetal growth restriction (FGR) is associated with adverse perinatal outcomes, but reliable diagnostic biomarkers are lacking. Through bioinformatics analysis of public datasets and clinical validation, we identified GAL and F2R as potential immune-related biomarkers associated with FGR. Both genes were consistently upregulated in FGR tissues and correlated with altered immune cell infiltration. These findings suggest that GAL and F2R may serve as diagnostic markers and potential therapeutic targets for FGR, facilitating early intervention and improved neonatal outcomes.

Indexed as

Health sciencesMedical specialtyMedicinePediatricsReproductive medicine

Identifiers

PMID41890958
PMCPMC13015252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.