Evidence map›Paper›PMID 41890825›Full record

ReviewJournal of pharmaceutical analysis2026

Recent advances in the analysis of unsaturated fatty acids in biological samples based on chemical derivatization and mass spectrometry techniques.

Yuanyuan Lin, Ningbo Chen, Wenda Chen, Fan Yin, Ling Yang, Xuan Chen, Jian-Liang Zhou, Tian Xie

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pharmaceutical analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuanyuan LinSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Ningbo ChenSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Wenda ChenSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Fan YinSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Ling YangSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Xuan ChenSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Jian-Liang ZhouSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.
Tian XieSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatty acids (FAs) play a vital role in various physiological processes in the human body, and the analysis of FA isomers is of utmost importance in the research of various diseases and FA metabolic pathways. Over the last few years, the use of chemical derivatization methods to alter the composition of FAs has been found to be highly effective in overcoming the drawback of poor sensitivity in mass spectrometry (MS) analysis due to the poor ionizability of functional groups in FA molecules. Furthermore, certain chemical derivatization methods have enabled detection of C=C and differentiation of

Indexed as

Carboxyl groupChemical derivatizationFatty acidsMass spectrometryUnsaturated C=C bonds

Identifiers

PMID41890825
PMCPMC13014655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.