Social factors are associated with disparities in epidemiological and operational indicators of COVID-19 surveillance in a region of the Brazilian Amazon.

Introduction: COVID-19 has caused substantial impacts on health, the economy, education, and quality of life worldwide, and pandemic control measures are directly associated with the quality of the pandemic response, which is essential for developing more assertive interventions for health promotion, treatment, and control of COVID-19. Objective: To evaluate epidemiological and operational indicators of COVID-19 surveillance in hospitalized patients in the state of Pará in 2021 by health mesoregion. Methodology: A cross-sectional, analytical, and ecological epidemiological study. Data were obtained from the Epidemiological Surveillance of Severe Acute Respiratory Syndrome through the Influenza Epidemiological Surveillance System (SIVEP-Gripe). Results: A total of 18,007 severe acute respiratory syndrome surveillance reports were included. In terms of incidence, there was a significant difference in the Lower Amazon, Southwest Pará, and Southeast Pará ( Conclusion: Differences were observed between health mesoregions in both epidemiological and operational indicators. The most affected mesoregions were the Lower Amazon, Southwest Pará, and Southeast Pará, which have high social vulnerability and are farther from the metropolitan area of Belém, where health services with better hospital and laboratory structures are concentrated.