ReviewJournal of clinical and experimental dentistry2026
Risk factors for dyseugia during chemotherapy in breast cancer women: A cohort STROBE-guided.
Review in Journal of clinical and experimental dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To evaluate the taste function of breast cancer patients undergoing Doxorubicin-Cyclophosphamide-Taxanes (AC-T) chemotherapy. Material and Methods: 68 breast cancer patients treated with AC-T were objectively (taste function) and subjectively (scales) evaluated in each chemotherapy cycle. Quality-of-life (QoL), other side effects, clinical-pathological and sociodemographic data, hematological test, general health scores, and the Body Mass Index (BMI) were additionally evaluated. ANOVA-RM/Bonferroni, Friedman/Dunn, chi-square/Fisher's exact tests were applied (SPSS 20.0, p<0.05). Results: There was a reduction in gustatory sensitivity (p<0.001), salivary flow (p<0.001), periodontal health (p<0.001), and QoL (p<0.001) from the third AC-T cycle and an increase in all side effects. There was an association between low taste sensitivity and lower BMI (p=0.008) and general health scores (p=0.006). Low gustatory sensitivity events was directly associated with the number of AC-T cycles (p<0.001), reduced salivary flow (p=0.019), poorer QoL (p<0.05), and a higher incidence of nausea and anorexia (p<0.05). In addition, age (p<0.001) and trastuzumab (p<0.001) were potential risk factors for dysgeusia. Conclusions: The incidence of dysgeusia is high in breast cancer patients treated with AC-T; it is cycle-dependent and is associated with weight loss, poorer QoL, and impaired oral and general health. The mechanisms involved in the use of trastuzumab should be investigated.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.