ReviewJournal of clinical and experimental dentistry2026
Prospective assessment on the cephalometric profile changes induced by labial hyaluronic acid infiltrations: A before-and-after study.
Review in Journal of clinical and experimental dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Background: Facial disharmonies are caused mainly by aging and malocclusions. Hyaluronic acid has been positioned as the dermal filler of choice for volume restoration. This study aimed to assess the effects of hyaluronic acid lip injections on facial profile and their durability. Material and Methods: A before-and-after study was carried out on 32 patients receiving hyaluronic acid lip infiltrations. A follow-up was scheduled at one-month intervals for three months, and at six months, in which four angular and two linear measurements were evaluated to determine changes in facial profile. These measurements consisted of the angle formed by lines Ls-N and L-N-Po; the angle between lines Li-N and L-N-Po; the angle subtended by lines Ls-Sn and Sn-Col; and the angle constructed from lines Li-Sn and Sn-Col. Likewise, the distance between point Ls and line SL, and the distance between point Li and line SL. Additionally, they were evaluated stratigraphically according to age ( 30 or >30 years) and volume ( 0.7 or > 0.7 mL). Results: Statistically significant results were obtained. A decrease of 5.76±9.81°, p <0.01, was found for Angle(Ls-Sn/Sn-Col). Additionally, the Distance (Ls-SL) showed a decline of 1.27 ± 2.11 mm, p < 0.01. Concerning the results stratified by infiltrated volume, greater angular changes were observed for volume >0.7ml, as well as for age, an increase of 3.06±6.81°,p<0.05 was gained for Angle(Li-N/N-Po), as a decrease of 2.91±1.80 mm, p<0.05 was observed for Distance(Ls-SL) in patients >30. Conclusions: The data revealed variability in angular and linear measurements among visits, indicating that final, sustained changes translated into aesthetic improvements. However, these results may vary depending on the volume injected and the patient's age.
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