Evidence map›Paper›PMID 41890665›Full record

ReviewJournal of clinical and experimental dentistry2026

Periodontitis, colorectal cancer and associated factors: A cross-sectional study.

Rosita Elena Espejo-Carrera, María Elizabeth Mendoza-Rubio, Carlos Alberto Minchón-Medina, César Abraham Vásquez-Plasencia, José Antonio Caballero-Alvarado, César León-Vega, Oscar Martín Del Castillo-Huertas, Angel Steven Asmat-Abanto

Abstract readReview
In one paragraph

Review in Journal of clinical and experimental dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosita Elena Espejo-CarreraMaster of Science in Clinical Research. Professor of Stomatology Study Program, Antenor Orrego Private University, Trujillo, Peru.
María Elizabeth Mendoza-RubioStudent of Stomatology Study Program, Antenor Orrego Private University, Trujillo, Peru.
Carlos Alberto Minchón-MedinaDoctor in Public Health. Director of Innovation and Technological Transfer. Professor of the Posgraduate School. Professor of Statistics Study Program. National University of Trujillo, Trujillo, Peru.
César Abraham Vásquez-PlasenciaMaster in Stomatology. Specialist in Periodontics. Professor of Stomatology Study Program, Antenor Orrego Private University, Trujillo, Peru.
José Antonio Caballero-AlvaradoSchool of Medicine, Antenor Orrego Private University, Trujillo, Peru. Department of Surgery, Regional Docente de Trujillo Hospital, Trujillo, Peru. PhD in Clinical and Translational Research.
César León-VegaProfessor of Human Medicine Study Program, Antenor Orrego Private University, Trujillo, Peru.
Oscar Martín Del Castillo-HuertasDoctor in Stomatology. Specialist in Orthodontics and Maxillary Orthopedics. Director of Stomatology Study Program, Antenor Orrego Private University, Trujillo, Peru.
Angel Steven Asmat-AbantoDoctor in Stomatology. Specialist in Periodontics. Professor of Human Medicine Study Program, Antenor Orrego Private University, Trujillo, Peru. Professor of Stomatology Study Program, Antenor Orrego Private University, Trujillo, Peru. Visiting Professor of Posgraduate School, Señor de Sipán University, Chiclayo, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontitis can cause systemic alterations associated with various oncological diseases, including colorectal cancer (CRC), with little information on this possible association and its related factors. Objectives: To determine the association between periodontitis severity, CRC, and related factors in adult patients. Material and Methods: This cross-sectional study was conducted between January and March 2025 at the Trujillo Regional Teaching Hospital and the "Dr. Luis Pinillos Ganoza" Regional Institute of Neoplastic Diseases - North IREN, Trujillo, Peru. A total of 320 adult patients were evaluated: 160 without colorectal cancer (non-CRC) and 160 with colorectal cancer (CRC). Inter- and intra-rater reliability was determined for the diagnosis of periodontitis, bleeding on probing (BOP), and dental plaque control (DPC). The corresponding specialist physician performed the diagnosis of colorectal cancer (CRC). Statistical analysis was performed using the Chi-square test, ordinal logistic regression, and binary logistic regression models, with a significance level of p < 0.05. Results: No association was found between the severity of periodontitis and CRC diagnosis in the evaluated population (p=0.068). The most common CRC stages were stage IV (48.1%) and stage III (39.4%), and the most common tumor locations were the rectum (40.0%) and sigmoid colon (36.3%). Conclusions: There is no association between the severity of periodontitis and CRC diagnosis.

Identifiers

PMID41890665
PMCPMC13016557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.