Evidence map›Paper›PMID 41890494›Full record

ArticleCureus2026

Nine Metachronous Cancers Primarily Involving the Head and Neck: A Case Report.

Atsushi Miyauchi, Shuichi Matsumoto, Hiroaki Ito, Masamitsu Hyodo, Masanori Teshima

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Atsushi MiyauchiOtolaryngology - Head and Neck Surgery, Kochi University, Nankoku, JPN.
Shuichi MatsumotoOtolaryngology - Head and Neck Surgery, Kochi University, Nankoku, JPN.
Hiroaki ItoOtolaryngology - Head and Neck Surgery, Kochi University, Nankoku, JPN.
Masamitsu HyodoOtolaryngology, Hosogi Hospital, Kochi, JPN.
Masanori TeshimaOtolaryngology - Head and Neck Surgery, Kochi University, Nankoku, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 62-year-old man presented with multiple malignant tumors, predominantly involving the head and neck region, including the esophagus, gum, oropharynx, larynx, lungs, and stomach. Histopathological analysis revealed that while the majority of the tumors were squamous cell carcinomas, other types including spindle cell carcinoma, mucoepidermoid carcinoma, and adenocarcinoma were also identified. Oropharyngeal cancer and oral cancer developed within a previously irradiated field from treatment 10 years prior. All subsequent primary tumors were detected at early stages through extensive multimodal surveillance, allowing for minimally invasive curative resections and contributing to long-term survival. This case underscores the necessity of lifelong, continuous monitoring for survivors of multiple primary cancers, as new malignancies can emerge long after initial treatments.

Indexed as

field cancerizationhead and neck cancermetachronous cancersmulticentric zonemultiple primary cancer

Identifiers

PMID41890494
PMCPMC13012888

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.